Occupational noise exposure at levels below those recognized as causing hearing impairment can cause annoyance and tiredness, and impair work performance. Few studies have addressed these and other responses to occupational noise of medium levels. Furthermore, studies typically explore one type of work place due to the hypothesized influence of situational factors. Our interest was to explore if a dose-response relationship between annoyance and measurements of sound levels in different work places could be derived. Four categories of occupational environments were studied; education, health care, offices and control rooms, including in total 26 work places. An average sound pressure level for each work place was derived from measurements at different positions in the rooms (range: 28.7 – 59.5 LpAeq dB). A global dose-response relationship between average A-weighted sound pressure levels and proportion of employees annoyed was found, despite disparity in conditions for the different categories of work places. Alternative descriptors of the sound pressure levels did not significantly improve the relationship. The result will be discussed in the view of impact of sound versus that of moderating factors.