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Multiple Kronecker RLS fusion-based link propagation for drug-side effect prediction
University Of Electronic Science And Technology Of China, Chengdu, China.
University of Nottingham Ningbo China, Ningbo, China.
Halmstad University, School of Information Technology.ORCID iD: 0000-0002-2851-4260
University Of Electronic Science And Technology Of China, Chengdu, China.ORCID iD: 0000-0003-2911-7643
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2024 (English)In: Transactions on Machine Learning Research, E-ISSN 2835-8856, Vol. 2024, p. 1-21Article in journal (Refereed) Published
Abstract [en]

Drug-side effect prediction has become an essential area of research in the field of pharma-cology. As the use of medications continues to rise, so does the importance of understanding and mitigating the potential risks associated with them. At present, researchers have turned to data-driven methods to predict drug-side effects. Drug-side effect prediction is a link prediction problem, and the related data can be described from various perspectives. To process these kinds of data, a multi-view method, called Multiple Kronecker RLS fusion-based link propagation (MKronRLSF-LP), is proposed. MKronRLSF-LP extends the Kron-RLS by finding the consensus partitions and multiple graph Laplacian constraints in the multi-view setting. Both of these multi-view settings contribute to a higher quality result. Extensive experiments have been conducted on drug-side effect datasets, and our empirical results provide evidence that our approach is effective and robust. © 2024, Transactions on Machine Learning Research. All rights reserved.

Place, publisher, year, edition, pages
New York: Transactions on Machine Learning Research , 2024. Vol. 2024, p. 1-21
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Computer and Information Sciences
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URN: urn:nbn:se:hh:diva-55636Scopus ID: 2-s2.0-85219546760OAI: oai:DiVA.org:hh-55636DiVA, id: diva2:1945269
Available from: 2025-03-18 Created: 2025-03-18 Last updated: 2025-10-01Bibliographically approved

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Tiwari, Prayag

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CiteExportLink to record
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