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A Microfluidic Platform for Synchrotron X-ray Studies of Proteins
MAX IV Laboratory, Lund University, Lund, Sweden.
MAX IV Laboratory, Lund University, Lund, Sweden.
MAX IV Laboratory, Lund University, Lund, Sweden.
MAX IV Laboratory, Lund University, Lund, Sweden.
Vise andre og tillknytning
2021 (engelsk)Konferansepaper, Oral presentation with published abstract (Fagfellevurdert)
Abstract [en]

New tools are needed to allow for complex protein dynamics studies, especially to study proteins in their native states. In the AdaptoCell project a microfluidic platform for academic and industrial users at MAX IV Laboratory is being developed. MAX IV is a Swedish national laboratory providing brilliant synchrotron X-rays for research. Due to the high photon flux, sensitive samples such as proteins are prone to rapid radiation damage; thus, it is advantageous to have the liquid sample underflow to refresh the sample continuously. This, in combination with small volumes, makes microfluidics a highly suitable sample environment for protein studies at MAX IV. The AdaptoCell platform is being integrated at three beamlines:Balder (X-ray absorption/emission spectroscopy), CoSAXS (small angle x-ray scattering) and Micromax (serial synchrotron crystallography). Currently, the platform is fully available atBalder, under commissioning at CoSAXS and being developed for MicroMAX.

sted, utgiver, år, opplag, sider
2021.
HSV kategori
Forskningsprogram
Smarta städer och samhällen
Identifikatorer
URN: urn:nbn:se:hh:diva-47661OAI: oai:DiVA.org:hh-47661DiVA, id: diva2:1686161
Konferanse
24th Swedish Conference on Macromolecular Structure and Function (SWEPROT), 20-23 June, 2021
Forskningsfinansiär
Swedish Foundation for Strategic Research, ITM-0375Tilgjengelig fra: 2022-08-08 Laget: 2022-08-08 Sist oppdatert: 2025-10-01bibliografisk kontrollert

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SWEPROT 2021(548 kB)86 nedlastinger
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Friel, R. J.

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