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  • 1.
    Verikas, Antanas
    et al.
    Halmstad University, School of Information Technology, Halmstad Embedded and Intelligent Systems Research (EIS). Kaunas University of Technology, Kaunas, Lithuania.
    Gelzinis, Adas
    Kaunas University of Technology, Kaunas, Lithuania.
    Bacauskiene, Marija
    Kaunas University of Technology, Kaunas, Lithuania.
    Hållander, Magnus
    Halmstad University, School of Information Technology, Halmstad Embedded and Intelligent Systems Research (EIS), Intelligent systems (IS-lab).
    Uloza, Virgilijus
    Kaunas University of Medicine, Kaunas, Lithuania.
    Kaseta, Marius
    Kaunas University of Medicine, Kaunas, Lithuania.
    Combining image, voice, and the patient's questionnaire data to categorize laryngeal disorders2010In: Artificial Intelligence in Medicine, ISSN 0933-3657, E-ISSN 1873-2860, Vol. 49, no 1, p. 43-50Article in journal (Refereed)
    Abstract [en]

    Objective: This paper is concerned with soft computing techniques for categorizing laryngeal disorders based on information extracted from an image of patient's vocal folds, a voice signal, and questionnaire data.

    Methods: Multiple feature sets are exploited to characterize images and voice signals. To characterize colour, texture, and geometry of biological structures seen in colour images of vocal folds, eight feature sets are used. Twelve feature sets are used to obtain a comprehensive characterization of a voice signal (the sustained phonation of the vowel sound /a/). Answers to 14 questions constitute the questionnaire feature set. A committee of support vector machines is designed for categorizing the image, voice, and query data represented by the multiple feature sets into the healthy, nodular and diffuse classes. Five alternatives to aggregate separate SVMs into a committee are explored. Feature selection and classifier design are combined into the same learning process based on genetic search.

    Results: Data of all the three modalities were available from 240 patients. Among those, 151 patients belong to the nodular class, 64 to the diffuse class and 25 to the healthy class. When using a single feature set to characterize each modality, the test set data classification accuracy of 75.0%, 72.1%, and 85.0% was obtained for the image, voice and questionnaire data, respectively. The use of multiple feature sets allowed to increase the accuracy to 89.5% and 87.7% for the image and voice data, respectively. The test set data classification accuracy of over 98.0% was obtained from a committee exploiting multiple feature sets from all the three modalities. The highest classification accuracy was achieved when using the SVM-based aggregation with hyper parameters of the SVM determined by genetic search. Bearing in mind the difficulty of the task, the obtained classification accuracy is rather encouraging.

    Conclusions: Combination of both multiple feature sets characterizing a single modality and the three modalities allowed to substantially improve the classification accuracy if compared to the highest accuracy obtained from a single feature set and a single modality. In spite of the unbalanced data sets used, the error rates obtained for the three classes were rather similar.

  • 2.
    Verikas, Antanas
    et al.
    Halmstad University, School of Information Science, Computer and Electrical Engineering (IDE), Halmstad Embedded and Intelligent Systems Research (EIS).
    Gelzinis, Adas
    Department of Applied Electronics, Kaunas University of Technology, LT-3031, Kaunas, Lithuania.
    Bacauskiene, Marija
    Department of Applied Electronics, Kaunas University of Technology, LT-3031, Kaunas, Lithuania.
    Uloza, Virgilijus
    Kaunas University of Medicine, Kaunas, Lithuania.
    Towards a computer-aided diagnosis system for vocal cord diseases2006In: Artificial Intelligence in Medicine, ISSN 0933-3657, E-ISSN 1873-2860, Vol. 36, no 1, p. 71-84Article in journal (Refereed)
    Abstract [en]

    OBJECTIVE: The objective of this work is to investigate a possibility of creating a computer-aided decision support system for an automated analysis of vocal cord images aiming to categorize diseases of vocal cords. METHODOLOGY: The problem is treated as a pattern recognition task. To obtain a concise and informative representation of a vocal cord image, colour, texture, and geometrical features are used. The representation is further analyzed by a pattern classifier categorizing the image into healthy, diffuse, and nodular classes. RESULTS: The approach developed was tested on 785 vocal cord images collected at the Department of Otolaryngology, Kaunas University of Medicine, Lithuania. A correct classification rate of over 87% was obtained when categorizing a set of unseen images into the aforementioned three classes. CONCLUSION: Bearing in mind the high similarity of the decision classes, the results obtained are rather encouraging and the developed tools could be very helpful for assuring objective analysis of the images of laryngeal diseases.

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