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  • 1.
    Adamsson, Viola
    et al.
    Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet.
    Reumark, Anna
    MSc Kostvetenskap Lantmännen Food R&D, Stockholm.
    Fredriksson, Ing-Britt
    SSK Mitt Hjärta, Bollnäs.
    Hammarström, Eskil
    SSK Mitt Hjärta, Bollnäs.
    Vessby, Bengt
    Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet.
    Johansson, Gunnar
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Riserus, Ulf
    Enheten för Klinisk Nutrition och Metabolism. Institutionen för Folkhälso- och vårdvetenskap. Uppsala Universitet.
    Effects of a Nordic diet on cardiovascular and metabolic risk factors in hypercholesterolemic subjects: a randomized controlled study2009Konferensbidrag (Refereegranskat)
    Abstract [en]

    Background: Apart from lipid-lowering drugs, dietary changes can also reduce plasma LDL-C concentrations. No studies have been conducted to investigate the clinical effects of a diet with traditional foods originating from the Nordic countries. Method: In a randomised, controlled parallel-group intervention study 88 mildly hypercholesterolemic men and women were randomized to either an ad libitum Nordic diet (ND) or a control diet (CD) for 6 weeks. All meals and foods were provided to the participants in the ND group. Primary outcome measure was LDL-cholesterol, and secondary outcomes were blood pressure, plasma insulin and glucose concentrations. The ND was a high-fibre diet rich in plant foods (fruit, berries, vegetables, root vegetables, whole grain cereals and legumes), vegetable fats (rapeseed oil and nuts) and fatty fish, low-fat milk products, but low in salt, added sugars, saturated fats and red meats. Result: 86 subjects completed the study. Distribution of carbohydrates, fat and protein (E%) in ND was 54, 27, 19, respectively. ND lowered plasma total cholesterol 0.98±0.75 mmol/l (-16%), LDL-C by 0.83±0.67 mmol/l (-21%), HDL-C 0.08±0.23 mmol/l (-5%), including reduced LDL/HDL ratio by -0.42±0.57 (-14%) (all p<0.01 versus controls). Insulin concentrations decreased by 0.51± 2.25 (-9%, p=0.01) and systolic blood pressure by 7±13 mmHg (-5%, P<0.01) compared to controls. Despite diets were eaten ad libitum, body weight decreased by 3.0 kg in the ND (P<0.001). No significant differences were found for diastolic blood pressure, triglycerides or plasma glucose. Conclusion: A Nordic diet improves blood lipid profile, and insulin sensitivity as well as lowering blood pressure to a clinically significant extent in hypercholesterolemic subjects.

  • 2.
    Adlers, Ann-Cathrine
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Att främja normal förlossning: Barnmorskans främsta uppgift2011Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    En graviditet och förlossning är i de allra flesta fall en normal livshändelse. De senaste decennierna har andelen instrumentella- och kejsarsnittsförlossningar ökat på bekostnad av den normala förlossningen. Trots fler interventioner ses ingen skillnad i den maternella och perinatala morbiditeten och mortaliteten. I barnmorskans arbetsområde ingår att handlägga den normala graviditeten och förlossningen. Syftet med studien var att beskriva hur barnmorskan kan främja en normal förlossning. Studien genomfördes som en litteraturstudie där 13 vetenskapliga artiklar, med både kvantitativ och kvalitativ ansats, analyserades. I resultatet framkom tre kategorier som beskriver hur barnmorskan främjar normal förlossning. Barnmorskan skapar genom närhet en god relation till kvinnan och ger vägledning. Genom att använda sig själv som kunskapskälla bidrar barnmorskans sinnen, erfarenheter av tidigare förlossningar och formell kunskap till att fatta korrekta beslut. Barnmorskan stödjer och bekräftar det normala individuellt efter kvinnans behov, vilket skapar en säker miljö runt kvinnan och förhindrar onödiga interventioner. Då det råder en medicinsk kultur inom förlossningsvården, behöver barnmorskans arbete kring normal förlossning stärkas. Forskning behövs på organisationsnivå, eftersom omgivande system inverkar på barnmorskans arbete med att främja den normala förlossningen.

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  • 3.
    Adlers, Ann-Cathrine
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Att verka som lots - Ett sätt för barnmorskan att främja normal förlossning2012Självständigt arbete på avancerad nivå (magisterexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Trots att majoriteten av alla graviditeter bedöms normala, ses en ökad frekvens av interventioner under förlossningsförloppet, där kejsarsnitt utan medicinsk indikation utgör en del. En orsak kan vara att vården av kvinnor med okomplicerad graviditet, bedrivs på samma nivå som en komplicerad graviditet. För både kvinnan och barnet kan ett kejsarsnitt leda till ökad risk för hälsoproblem. I barnmorskans ansvarsområde ingår att självständigt handlägga vården vid normal, okomplicerad graviditet och förlossning. Barnmorskan har i sitt arbete även möjlighet att verka för att främja kvinnors hälsa. Syftet med studien var att öka förståelsen för hur förlossningsbarnmorskor främjar den normala förlossningsprocessen. En icke deltagande observationsstudie, av sammanlagt fyra barnmorskor i verksamhet på förlossningsavdelning, genomfördes vid två sjukhus. Grounded Theory användes som metod för datainsamling och analys. Som resultat framkom kärnkategorin att verka som lots samt fyra underkategorier. Primärt skapar och förankrar barnmorskan en relation med kvinnan. Genom förlossningens olika faser bedömer, underlättar och bekräftar barnmorskan förlossningsförloppet individuellt efter kvinnans behov. Kategorierna formar tillsammans en modell som beskriver vad barnmorskan utför; i verbal och i tyst kommunikation och i att agera eller att avstå från att agera, för att främja en normal förlossning. Behov finns av fortsatt forskning kring vad i barnmorskans handläggning av förlossningsprocessen som gynnar den normala förlossningen. Det är även väsentligt med forskning på organisationsnivå då det inverkar på hur barnmorskan främjar den normala förlossningen.

  • 4.
    Afifi, Mustafa
    et al.
    Department of Non-Communicable Diseases Control, Ministry of Health (HQ), Muscat, Oman.
    von Bothmer, Margareta
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Egyptian women's attitudes and beliefs about female genital cutting and its association with childhood maltreatment2007Ingår i: Nursing and Health Sciences, ISSN 1441-0745, E-ISSN 1442-2018, Vol. 9, nr 4, s. 270-276Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This study aimed to establish Egyptian women's attitudes and beliefs about female genital cutting (FGC) or mutilation by applying a questionnaire module about violence to a subsample of 5249 married women from a total of 19 474 women who participated in the 2005 Egypt Demographic Health Survey. Women were interviewed to determine if they had been exposed to marital violence in the year prior to the survey, their attitudes and beliefs about FGC, and if they physically abused their children. The association of beliefs about FGC with maternal physical abuse was examined, adjusting for exposure to marital violence and other socio-demographic variables. Of the women surveyed 16.4% and 3.4% had been exposed to physical and sexual violence, respectively, during the year prior to the survey. Around 76% of the women surveyed intended to continue the FGC practice, and 69.8% had slapped or hit their children during the year prior to the survey. Holding positive beliefs about the practice of FGC or intending to continue it was associated with maternal physical abuse and this has significant implications for health and welfare workers in Egypt and for society in general.

  • 5.
    Aghanavesi, Somayeh
    et al.
    School of Technology and Business Studies, Dalarna University, Falun 78188, Sweden.
    Fleyeh, Hasan
    School of Technology and Business Studies, Dalarna University, Falun 78188, Sweden.
    Dougherty, Mark
    Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS).
    Feasibility of Using Dynamic Time Warping to Measure Motor States in Parkinson’s Disease2020Ingår i: Journal of Sensors, ISSN 1687-725X, E-ISSN 1687-7268, s. 1-14, artikel-id 3265795Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this paper is to investigate the feasibility of using the Dynamic Time Warping (DTW) method to measure motor states in advanced Parkinson's disease (PD). Data were collected from 19 PD patients who experimented leg agility motor tests with motion sensors on their ankles once before and multiple times after an administration of 150% of their normal daily dose of medication. Experiments of 22 healthy controls were included. Three movement disorder specialists rated the motor states of the patients according to Treatment Response Scale (TRS) using recorded videos of the experiments. A DTW-based motor state distance score (DDS) was constructed using the acceleration and gyroscope signals collected during leg agility motor tests. Mean DDS showed similar trends to mean TRS scores across the test occasions. Mean DDS was able to differentiate between PD patients at Off and On motor states. DDS was able to classify the motor state changes with good accuracy (82%). The PD patients who showed more response to medication were selected using the TRS scale, and the most related DTW-based features to their TRS scores were investigated. There were individual DTW-based features identified for each patient. In conclusion, the DTW method can provide information about motor states of advanced PD patients which can be used in the development of methods for automatic motor scoring of PD. © 2020 Somayeh Aghanavesi et al.

  • 6.
    Agvall, Björn
    et al.
    Halland Hospital Halmstad, Halmstad, Sweden.
    Ashfaq, Awais
    Högskolan i Halmstad, Akademin för informationsteknologi.
    Bjurström, Karl
    Halland Hospital Halmstad, Halmstad, Sweden.
    Etminani, Kobra
    Högskolan i Halmstad, Akademin för informationsteknologi.
    Friberg, Lovisa
    AstraZeneca, Stockholm, Sweden.
    Lidén, Johanna
    AstraZeneca, Stockholm, Sweden.
    Lingman, Markus
    Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Halland Hospital, Region Halland, Halmstad, Sweden.
    Characteristics, management and outcomes in patients with CKD in a healthcare region in Sweden: a population-based, observational study2023Ingår i: BMJ Open, E-ISSN 2044-6055, Vol. 13, nr 7, artikel-id e069313Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives: To describe chronic kidney disease (CKD) regarding treatment rates, comorbidities, usage of CKD International Classification of Diseases (ICD) diagnosis, mortality, hospitalisation, evaluate healthcare utilisation and screening for CKD in relation to new nationwide CKD guidelines.

    Design: Population-based observational study.

    Setting: Healthcare registry data of patients in Southwest Sweden.

    Participants: A total cohort of 65 959 individuals aged >18 years of which 20 488 met the criteria for CKD (cohort 1) and 45 470 at risk of CKD (cohort 2).

    Primary and secondary outcome measures: Data were analysed with regards to prevalence, screening rates of blood pressure, glucose, estimated glomerular filtration rate (eGFR), Urinary-albumin-creatinine ratio (UACR) and usage of ICD-codes for CKD. Mortality and hospitalisation were analysed with logistic regression models.

    Results: Of the CKD cohort, 18% had CKD ICD-diagnosis and were followed annually for blood pressure (79%), glucose testing (76%), eGFR (65%), UACR (24%). UACR follow-up was two times as common in hypertensive and cardiovascular versus diabetes patients with CKD with a similar pattern in those at risk of CKD. Statin and renin-angiotensin-aldosterone inhibitor appeared in 34% and 43%, respectively. Mortality OR at CKD stage 5 was 1.23 (CI 0.68 to 0.87), diabetes 1.20 (CI 1.04 to 1.38), hypertension 1.63 (CI 1.42 to 1.88), atherosclerotic cardiovascular disease (ASCVD) 1.84 (CI 1.62 to 2.09) associated with highest mortality risk. Hospitalisation OR in CKD stage 5 was 1.96 (CI 1.40 to 2.76), diabetes 1.15 (CI 1.06 to 1.25), hypertension 1.23 (CI 1.13 to 1.33) and ASCVD 1.52 (CI 1.41 to 1.64).

    Conclusions: The gap between patients with CKD by definition versus those diagnosed as such was large. Compared with recommendations patients with CKD have suboptimal follow-up and treatment with renin-angiotensin-aldosterone system inhibitor and statins. Hypertension, diabetes and ASCVD were associated with increased mortality and hospitalisation. Improved screening and diagnosis of CKD, identification and management of risk factors and kidney protective treatment could affect clinical and economic outcomes. © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

  • 7.
    Agvall, Björn
    et al.
    Region Halland, Halmstad, Sweden; Center for Primary Health Care Research, Lund University, Malmö, Sweden.
    Jonasson, Junmei Miao
    Region Halland, Halmstad, Sweden; University of Gothenburg, Gothenburg, Sweden.
    Galozy, Alexander
    Högskolan i Halmstad, Akademin för informationsteknologi.
    Halling, Anders
    Center for Primary Health Care Research, Lund University, Malmö, Sweden.
    Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study2024Ingår i: Cardiovascular Diabetology, E-ISSN 1475-2840, Vol. 23, nr 1, artikel-id 124Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Individuals with type 2 diabetes (T2D) are at increased risk of developing cardiovascular disease (CVD) which necessitates monitoring of risk factors and appropriate pharmacotherapy. This study aimed to identify factors predicting emergency department visits, hospitalizations, and mortality among T2D patients after being newly diagnosed with CVD.

    Methods: In a retrospective observational study conducted in Region Halland, individuals aged > 40 years with T2D diagnosed between 2011 and 2019, and a new diagnosis of CVD between 2016 and 2019, were followed for one year from the date of CVD diagnosis. The first encounter for CVD diagnosis was categorized as inpatient-, outpatient-, primary-, or emergency department care. Follow-up included laboratory tests, blood pressure, pharmacotherapies, and healthcare utilization. Hazard ratios (HR) in two Cox regression analyses determined relative risks for emergency visits/hospitalization and mortality, adjusting for age, sex, glucose regulation, lipid levels, kidney function, blood pressure, pharmacotherapy, and healthcare utilization.

    Results: The study included a total of 1759 T2D individuals who received a new CVD diagnosis, with 67% diagnosed during inpatient care. The average hospitalization stay was 6.5 days, and primary care follow-up averaged 10.1 visits. Patients with CVD diagnosed in primary care had a HR 0.52 (confidence interval [CI] 0.35–0.77) for emergency department visits/hospitalization, but age had a HR 1.02 (CI 1.00-1.03). Pharmacotherapy with insulin, DPP4-inhibitors, aldosterone antagonists, and beta-blockers had a raised HR. Highest mortality risk was observed when CVD was diagnosed inpatient care, systolic blood pressure < 100 mm Hg and elevated HbA1c. Age had a HR 1.05 (CI 1.03–1.08), eGFR < 30 ml/min HR 1.46 (CI 1.01–2.11), and LDL-Cholesterol > 2,5 h 1.46 (CI 1.01–2.11) and associated with increased mortality risk. Pharmacotherapy with metformin had a HR 0.41 (CI 0.28–0.62), statins a HR 0.39 (CI 0.27–0.57), and a primary care follow-up < 30 days a HR 0.53 (CI 0.37–0.77) and associated with lower mortality risk.

    Conclusions: T2D individuals who had a new diagnosis of CVD were predominantly diagnosed when hospitalized, while follow-up typically occurred in primary care. Identifying factors that predict risks of mortality and hospitalization should be a focus of follow-up care, underscoring the critical role of primary care in the effective management of T2D and CVD. © The Author(s) 2024.

  • 8.
    Aili, Katarina
    et al.
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Hälsa och idrott. Spenshult Research and Development Center, Halmstad, Sweden | Karolinska Institutet, Institute of Environmental Medicine, Stockholm, Sweden.
    Campbell, Paul
    Keele University, School for Primary, Community and Social Care, Keele, United Kingdom | Midlands Partnership NHS Foundation Trust, Stafford, United Kingdom.
    Michaleff, Zoe A.
    Keele University, School for Primary, Community and Social Care, Keele, United Kingdom.
    Strauss, Vicky Y.
    University of Oxford, CSM, NDORMS, Oxford, United Kingdom.
    Jordan, Kelvin P.
    Keele University, School for Primary, Community and Social Care, Keele, United Kingdom | Keele University, Centre for Prognosis Research, Keele, United Kingdom.
    Bremander, Ann
    Spenshult Research and Development Center, Halmstad, Sweden | Department of Regional Health Research, University of Southern Denmark, Odense, Denmark.
    Croft, Peter
    Keele University, School for Primary, Community and Social Care, Keele, United Kingdom | Keele University, Centre for Prognosis Research, Keele, United Kingdom.
    Bergman, Stefan
    Spenshult Research and Development Center, Halmstad, Sweden | University of Gothenburg, Institute of Medicine, Gothenburg, Sweden.
    Long-term trajectories of chronic musculoskeletal pain: a 21-year prospective cohort latent class analysis2021Ingår i: Pain, ISSN 0304-3959, E-ISSN 1872-6623, Vol. 162, nr 5, s. 1511-1520Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    ABSTRACT: Our knowledge of the prevalence, impact, and outcomes of chronic pain in the general population is predominantly based on studies over relatively short periods of time. The aim of this study was to identify and describe trajectories of the chronic pain status over a period of 21 years. Self-reported population data (n = 1858) from 5 timepoints were analyzed. Pain was categorized by: no chronic pain (NCP), chronic regional pain (CRP), and chronic widespread pain (CWP). Latent class growth analysis was performed for identification of trajectories and logistic regression analysis for identification of predictors for pain prognosis. Five trajectories were identified: (1) persistent NCP (57%), (2) migrating from NCP to CRP or CWP (5%), (3) persistent CRP or migration between CRP and NCP (22%), (4) migration from CRP to CWP (10%), and (5) persistent CWP (6%). Age, sleeping problems, poor vitality, and physical function at baseline were associated with pain progression from NCP. Female gender, seeking care for pain, lack of social support, poor physical function, vitality, and mental health predicted poor pain prognosis among those with CRP. In conclusion, chronic pain was common in the population including 6% reporting persistent CWP, although the majority persistently reported NCP. Most people had stable pain status, but some had ongoing change in pain status over time including people who improved from chronic pain. It was possible to identify clinically relevant factors, characterizing trajectories of chronic pain development, that can be useful for identifying individuals at risk and potential targets for intervention. Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the International Association for the Study of Pain.

  • 9.
    Aili, Katarina
    et al.
    Högskolan i Halmstad, Akademin för hälsa och välfärd.
    Nygren, Jens M.
    Högskolan i Halmstad, Akademin för hälsa och välfärd.
    Arvidsson, Susann
    Högskolan i Halmstad, Akademin för hälsa och välfärd.
    Olsson, Maria
    Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Jarfelt, Marianne
    Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Health Outcomes in Adult Survivors of Childhood All and Their Siblings – A National Long Term Follow Up2022Ingår i: Pediatric Blood & Cancer, ISSN 1545-5009, E-ISSN 1545-5017, Vol. 69, nr S5, s. S173-S173, artikel-id e29952Artikel i tidskrift (Refereegranskat)
  • 10.
    Albinsson, John
    et al.
    Lund Univ, Dept Biomed Engn, S-22100 Lund, Sweden..
    Brorsson, Sofia
    Högskolan i Halmstad, Akademin för ekonomi, teknik och naturvetenskap, Rydberglaboratoriet för tillämpad naturvetenskap (RLAS).
    Rydén Ahlgren, Åsa
    Lund Univ, Dept Clin Sci, Clin Physiol & Nucl Med Unit, Malmo, Sweden..
    Cinthio, Magnus
    Lund Univ, Dept Biomed Engn, S-22100 Lund, Sweden..
    Improved tracking performance of lagrangian block-matching methodologies using block expansion in the time domain: In silico, phantom and invivo evaluations2014Ingår i: Ultrasound in Medicine and Biology, ISSN 0301-5629, E-ISSN 1879-291X, Vol. 40, nr 10, s. 2508-2520Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this study was to evaluate tracking performance when an extra reference block is added to a basic block-matching method, where the two reference blocks originate from two consecutive ultrasound frames. The use of an extra reference block was evaluated for two putative benefits: (i) an increase in tracking performance while maintaining the size of the reference blocks, evaluated using in silico and phantom cine loops; (ii) a reduction in the size of the reference blocks while maintaining the tracking performance, evaluated using in vivo cine loops of the common carotid artery where the longitudinal movement of the wall was estimated. The results indicated that tracking accuracy improved (mean - 48%, p<0.005 [in silico]; mean - 43%, p<0.01 [phantom]), and there was a reduction in size of the reference blocks while maintaining tracking performance (mean - 19%, p<0.01 [in vivo]). This novel method will facilitate further exploration of the longitudinal movement of the arterial wall. (C) 2014 World Federation for Ultrasound in Medicine & Biology.

  • 11.
    Alfakir, Omar
    et al.
    Högskolan i Halmstad, Akademin för informationsteknologi.
    Larsson, Viktor
    Högskolan i Halmstad, Akademin för informationsteknologi.
    Alonso-Fernandez, Fernando
    Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS).
    A Cross-Platform Mobile Application for Ambulance CPR during Cardiac Arrests2021Ingår i: 2021 8th International Conference on Soft Computing & Machine Intelligence (ISCMI), Piscataway: IEEE, 2021, s. 120-124Konferensbidrag (Refereegranskat)
    Abstract [en]

    This paper describes the implementation of a cross-platform software application to aid ambulance paramedics during CPR (Cardio-Pulmonary Resuscitation). It must be able to work both on iOS and Android devices, which are the leading platforms in the mobile industry. The goal of the application is to guide paramedics in the different processes and expected medication to be administered during a cardiac arrest, a scenario that is usually stressful and fast-paced, thus prone to errors or distractions. The tool must provide timely reminders of the different actions to be performed during a cardiac arrest, and in an appropriate order, based on the results of the previous actions. A timer function will also control the duration of each step of the CPR procedure. The application is implemented in React Native which, using JavaScript as programming language, allows to deploy applications that can run both in iOS and Android native languages. Our solution could also serve as a record of events that could be transmitted (even in real-time) to the hospital without demanding explicit verbal communication of the procedures or medications administered to the patient during the ambulance trip. This would provide even higher efficiency in the process, and would allow automatic incorporation of the events to the medical record of the patient as well. © 2021 IEEE.

  • 12.
    Allheeib, Nasser
    et al.
    King Saud University, Riyadh, Saudi Arabia.
    Kanwal, Summrina
    Högskolan i Halmstad, Akademin för informationsteknologi, Centrum för forskning om tillämpade intelligenta system (CAISR).
    Alamri, Sultan
    Saudi Electronic University, Riyadh, Saudi Arabia.
    An Intelligent Heart Disease Prediction Framework Using Machine Learning and Deep Learning Techniques2023Ingår i: International Journal of Data Warehousing and Mining, ISSN 1548-3924, E-ISSN 1548-3932, Vol. 19, nr 1, s. 1-24Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Cardiovascular diseases (CVD) rank among the leading global causes of mortality. Early detection and diagnosis are paramount in minimizing their impact. The application of ML and DL in classifying the occurrence of cardiovascular diseases holds significant potential for reducing diagnostic errors. This research endeavors to construct a model capable of accurately predicting cardiovascular diseases, thereby mitigating the fatality associated with CVD. In this paper, the authors introduce a novel approach that combines an artificial intelligence network (AIN)-based feature selection (FS) technique with cutting-edge DL and ML classifiers for the early detection of heart diseases based on patient medical histories. The proposed model is rigorously evaluated using two real-world datasets sourced from the University of California. The authors conduct extensive data preprocessing and analysis, and the findings from this study demonstrate that the proposed methodology surpasses the performance of existing state-of-the-art methods, achieving an exceptional accuracy rate of 99.99%. © 2023 IGI Global. All rights reserved.

  • 13.
    Allisson, Anna
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    När återhämtar patienten sig snabbast?: Jämförlse mellan inhalationsanestesi och total intravenös anestesi.2010Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Generell anestesi kan ges som inhalationsanestesi eller total intravenös anestesi (TIVA). En förutsägbar anestesi med snabbt uppvaknande och bibehållen vakenhet är en högt önskvärd egenskap oavsett anestesiform. Det råder en klinisk och vetenskaplig diskussion om vilken anestesiform som ger snabbast tidig postoperativ återhämtning. syftet med studien var att jämföra patienters tidiga postoperativa återhämtning efter inhalationsanestesi respektive efter total intravenös anestesi (TIVA). Metoden var en litteraturstudie baserad på 15 vetenskapliga artiklar. Dessa analyserades utifrån frågeställningen: Vilken anestesiform som ger den snabbaste tidiga postoperativa återhämtningen. Det framkom en indelning av resultatet i tre kategorier: snabbare tidig postoperativ återhämtning efter inhalationsanestesi, lika lång tid till återhämtning efter inhalationsanestesi som efter TIVA samt snabbare tidig postoperativ återhämtning efter TIVA. Resultatet visade att inhalationsanestesi gav snabbast tdiig postoperativ återhämtning. Anestesisjuksköterskans handhavande, planering och erfarenhet påverkar patientens uppvakande. därför skulle vidare forskning istället jämföra dessa båda anestesiformer på ett annat sätt. Tiden kunde istället mätas från det att anestesisjukskäterskan extuberat patienten och till payienten verkar adekvat orienterad för att erhålla ett mer jämförbart resultat.

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    FULLTEXT03
  • 14.
    Almqvist-Tangen, Gerd
    et al.
    Child Health Care Team, County Council Halland, Sweden & Department of Paediatrics, University of Gothenburg, Gothenburg, Sweden.
    Bergman, Stefan
    Research and Development Centre, Spenshult Hospital, Oskarström, Sweden.
    Dahlgren, Jovanna
    Department of Paediatrics, University of Gothenburg, Gothenburg, Sweden.
    Roswall, Josefine
    Department of Paediatrics, County Hospital, Halmstad, Sweden & Department of Paediatrics, University of Gothenburg, Gothenburg, Sweden.
    Alm, Bernt
    Child Health Care Team, County Council Halland, Sweden & Department of Paediatrics, University of Gothenburg, Gothenburg, Sweden.
    Factors associated with discontinuation of breastfeeding before 1 month of age2012Ingår i: Acta Paediatrica, ISSN 0803-5253, E-ISSN 1651-2227, Vol. 101, nr 1, s. 55-60Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Breastfeeding is associated with many benefits for both mother and child. Initiation rates are high in Sweden. Recently a slight decline is seen.

    AIM: The aim of this study was to assess factors associated with discontinuation of breastfeeding during the first 4 weeks.

    METHOD: A population-based longitudinal birth cohort study recruiting from 2007 to 2008 in south-western Sweden. At the first visit to the child health centre, parents were asked to complete a questionnaire. Also, the infants' height, weight, head and waist circumference were collected. Response rate was 69.2%.

    RESULTS: Twenty-seven per cent of mothers had breastfeeding problems. In a multivariate analysis, there was a negative correlation between breastfeeding and use of pacifier (OR 3.72; CI 2.09-6.63), maternal smoking (OR 2.09; CI 1.08-4.05) and breastfeeding problems (OR 2.54; CI 1.73-3.71). Breastfeeding problems were correlated with poor sucking technique (OR 2.96; CI 2.14-4.07), support from maternity ward (OR 2.56; CI 2.05-3.19) and perceived poor weight gain (OR 1.37; CI 1.00-1.86).

    CONCLUSION: Many mothers reported breastfeeding problems that are associated with an early cessation. This is preventable with support, but the timing is crucial. To promote breastfeeding, the support from the child health centres must be tailored with the maternal perspective in mind.

    © 2011 Foundation Acta Pædiatrica

  • 15.
    Amirahmadi, S. F.
    et al.
    Monash University, Clayton, Victoria, Australia.
    Whittingham, S.
    Monash University, Clayton, Victoria, Australia.
    Crombie, D. E.
    Monash University, Clayton, Victoria, Australia.
    Nandakumar, Kutty Selva
    Lund University, Lund, Sweden.
    Holmdahl, R.
    Lund University, Lund, Sweden.
    Mackay, I. R.
    Monash University, Clayton, Victoria, Australia.
    van Damme, M. P.
    Monash University, Clayton, Victoria, Australia.
    Rowley, M. J.
    Monash University, Clayton, Victoria, Australia.
    Arthritogenic anti-type II collagen antibodies are pathogenic for cartilage-derived chondrocytes independent of inflammatory cells2005Ingår i: Arthritis and Rheumatism, ISSN 0004-3591, E-ISSN 1529-0131, Vol. 52, nr 6, s. 1897-1906Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: Some monoclonal antibodies (mAb) to type II collagen (CII) are arthritogenic upon passive transfer to mice. We undertook this study to investigate whether such mAb are pathogenic in the absence of mediators of inflammation. METHODS: The arthritogenic mAb CIIC1 and M2139, and the nonarthritogenic mAb CIIF4, each reactive with a distinct and well-defined conformational epitope on CII, were compared with control mAb GAD6. Bovine chondrocytes were cultured with one of the mAb, and on days 3, 6, and 9, antibody binding by chondrocytes and newly synthesized extracellular matrix (ECM) was examined by immunofluorescence, morphologic effects were studied by electron microscopy, and synthesis of matrix components was determined by metabolic labeling with (3)H-proline for collagen and (35)S-sulfate for proteoglycans. RESULTS: All 3 mAb to CII bound to the matrix. CIIC1 and M2139 adversely affected the cultures, whereas CIIF4 did not. CIIC1 caused disorganization of CII fibrils in the ECM without affecting chondrocyte morphology, and increased matrix synthesis. M2139 caused thickening and aggregation of CII fibrils in the ECM and abnormal chondrocyte morphology but matrix synthesis was unaffected. CONCLUSION: The unique arthritogenic capacity of particular anti-CII mAb upon passive transfer could be explained by their adverse, albeit differing, effects in primary cultures of chondrocytes. Such effects occur independent of inflammation mediators and are related to the epitope specificity of the mAb. Interference with the structural integrity of CII could precede, and even initiate, the inflammatory expression of disease.

  • 16.
    Andersen, Sara
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Johannesson, Caroline
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Det finns inget kvar att erövra: Upplevelse av att leva med myelom2011Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Myleom är en cancersjukdom som uppkommer i benmärgen. I Sverige insjuknar ungefär 500-600 personer i myelom per år. Syftet med litteraturstudien var att med hjälp av de sex dimensionerna av smärta belysa upplevelsen av att leva med sjukdomen myelom. Studien genomfördes utifrån en teoretisk referensram. För att få en helhetsbild av individernas upplevelser av sjukdomen redovisas resultatet utifrån sex dimensioner av smärta. Resultatet visar att individer med myelom får ett inskränkt socialt liv, förändrade vanor och både fysisk och psykisk ohälsa. Individerna påverkas av smärta, trötthet och upprepade infektioner som orsakas av ett nedsatt immunförsvar. Då kunskap om sjukdomen i samhället är begränsad får individer med myelom minskad förståelse när det gäller sjukdomsbilden. För att sjuksköterskan skall få förståelse för individerna och deras livskvalitet krävs en adekvat smärtbedömning, som bör beröra hur individen påverkas av sin sjukdom i det vardagliga livet. Mer forskning kring sjukdomen, behandlingar och mediciner behövs och det vore önskvärt om målet vore att sjukdomen skall kunna botas.

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  • 17.
    Andersson, Frida
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Bodén, Anna
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Käll, Elin
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    En förändrad framtid – Kvinnors upplevelser av att behandlats för cervixcancer2010Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Sedan 1960 talet har screening för och vaccinering mot cervixcancer blivit allt mer utbrett, trots detta drabbas fortfarande 450 kvinnor varje år av cervixcancer i Sverige. Då incidensen minskar finns risken för att kunskapen om sjukdomen minskar. Syftet var därför att belysa kvinnors upplevelser av att behandlats för cervixcancer för att öka kunskap och förståelse i mötet med kvinnorna. Studien utfördes som en litteraturstudie där 20 artiklar låg till grund för resultatet. Resultatet belyser kvinnors upplevelser av att behandlats för cervixcancer och hur det påverkade vardagen, reproduktiv och sexuell hälsa, deras syn på framtiden samt hur de upplevde sjukvården. Att ha behandlats för cervixcancer var något som drabbade hela människan, såväl fysiskt, psykiskt som sexuellt och inte bara genitalierna där sjukdomen hade sitt ursprung. Det framkom att kvinnorna ville samtala om tabubelagda ämnena men inte alltid vågade ta upp dem själva. Därför är det betydelsefullt att sjuksköterskorna ställer frågor angående de här ämnena. Omvårdnad bör grundas på evidens och därför är det viktigt att forskningen fortskrider för att optimera vården för kvinnor med cervixcancer.

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  • 18.
    Andersson, M.
    et al.
    Lund University, Lund, Sweden; Spenshult Research & Development Centre, Halmstad, Sweden.
    Bremander, Ann
    Lund University, Lund, Sweden; Spenshult Research & Development Centre, Halmstad, Sweden; University of Southern Denmark, Odense, Denmark; University Hospital of Southern Denmark, Sonderborg, Denmark.
    Larsson, Ingrid
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Spenshult Research & Development Centre, Halmstad, Sweden.
    Empowerment and Associations to Disease Activity and Pain in Patients with Rheumatoid Arthritis2021Ingår i: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 80, nr Supplement 1, s. 197-197Artikel i tidskrift (Refereegranskat)
  • 19.
    Andersson, Maria L E
    et al.
    Lund University, Lund, Sweden; Spenshult Research and Development Centre, Halmstad, Sweden.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. Lund University, Lund, Sweden.
    Aili, Katarina
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Karolinska Institute, Stockholm, Sweden.
    Bremander, Ann
    University of Southern Denmark, Odense, Denmark; University Hospital of Southern Denmark, Sonderborg, Denmark.
    Bergman, Stefan
    Spenshult Research and Development Centre, Halmstad, Sweden; University of Gothenburg, Gothenburg, Sweden.
    Cohort profile: the Halland osteoarthritis (HALLOA) cohort–from knee pain to osteoarthritis: a longitudinal observational study in Sweden2022Ingår i: BMJ Open, E-ISSN 2044-6055, Vol. 12, nr 7, artikel-id e057086Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: The overall objective in this study is to investigate the early development of radiographic knee osteoarthritis (OA) and its association with hand or/and knee OA, metabolic diseases, biomarkers, chronic pain, physical function and daily physical activity types.

    Participants: The Halland osteoarthritis (HALLOA) cohort is a longitudinal cohort study that includes individuals with knee pain in the southwest of Sweden. Enrolment took place from 2017 to 2019. The inclusion criteria were current knee pain, with no former known radiographic knee OA and no cruciate ligament rupture or rheumatological disorder. The participants were recruited: (1) when seeking care for knee pain in primary healthcare or (2) by advertisements in local newspapers. There are 306 individuals included in the study, mean age (SD) 51.7 (8.7) years and 69% are women. The baseline and follow-ups include clinical tests, radiographical examinations, blood samples, metabolic measures, pain pressure thresholds, tests of physical functions, daily physical activity types and patient-reported outcomes.

    Findings to date: There were associations between metabolic factors and radiographic knee OA, even in those with normal body mass index at baseline. In addition, clinical hand OA was positively associated with fasting plasma glucose. We also found that modifiable factors as increased visceral fat and total body fat were associated with increased pain sensitivity among individuals with knee pain.

    Future plans: By studying possible pathophysiological mechanisms of OA over time, we aim to provide new insights on OA progression, identify usable preventive measures helping the clinicians in the management of the disease and improve health for the patients. It is also important to study the development of chronic pain in OA, to get tools to identify individuals at risk and to be able to offer them treatment.

     © Author(s) (or their employer(s)) 2022. 

  • 20.
    Andersson, Maria L.E.
    et al.
    Department of Clinical Sciences Lund, Lund, Sweden; Spenshult Research and Development Centre, Halmstad, Sweden.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. Department of Clinical Sciences Lund, Lund, Sweden; Spenshult Research and Development Centre, Halmstad, Sweden.
    Aili, Katarina
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Spenshult Research and Development Centre, Halmstad, Sweden; Karolinska Institutet, Stockholm, Sweden.
    Bremander, Ann
    Department of Clinical Sciences Lund, Lund, Sweden; Spenshult Research And Development Centre, Halmstad, Sweden; University Of Southern Denmark, Odense, Denmark; University Hospital of Southern Denmark, Sonderborg, Denmark.
    Bergman, Stefan
    Spenshult Research And Development Centre, Halmstad, Sweden; Sahlgrenska Academy, Gothenburg, Sweden.
    Associations between metabolic factors and radiographic knee osteoarthritis in early disease - a cross-sectional study of individuals with knee pain2022Ingår i: BMC Musculoskeletal Disorders, E-ISSN 1471-2474, Vol. 23, nr 1, artikel-id 938Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: Metabolic factors have been shown to be associated to severe radiographic knee osteoarthritis (RKOA). However, more knowledge is needed in early clinical knee osteoarthritis (KOA). The aim was to study associations between metabolic factors and radiographic knee osteoarthritis (OA) in individuals with knee pain. A second aim was to study associations between metabolic factors and RKOA in those with normal BMI and in those overweight/obese, respectively. Method: This cross-sectional study included 282 individuals with knee pain (without cruciate ligament injury) and aged 30–67 years, and 70% women. Waist circumference, body mass index (BMI), proportion of fat and visceral fat area (VFA) were assessed. RKOA was defined as Ahlbäck grade 1 in at least one knee. Fasting blood samples were taken and triglycerides, cholesterol (total, low density lipoprotein (LDL) and high density lipoprotein (HDL)), C-reactive protein (CRP), glucose, HbA1C were analysed. Metabolic syndrome was defined in accordance with the International Diabetes Federation (IDF). Associations were analysed by logistic regression. Results: Individuals with RKOA were older, had higher BMI, higher VFA, larger waist circumference and had increased total cholesterol, triglycerides and LDL-cholesterol, but not fasting glucose. There was no difference between the group with RKOA vs. non-radiographic group regarding the presence of metabolic syndrome. In a subgroup analysis of individuals with normal BMI (n = 126), those with RKOA had higher VFA, more central obesity, higher levels of CRP and total cholesterol, compared with individuals without RKOA. In individuals with obesity, age was the only outcome associated to RKOA. Conclusion: There were clear associations between metabolic factors and RKOA in individuals with knee pain, also in those with normal BMI. In individuals with obesity age was the only variable associated to RKOA. Trial registration:: clinicalTrials.gov Identifier: NCT04928170. © 2022, The Author(s).

  • 21.
    Andersson, Maria L.E.
    et al.
    Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden | Spenshult research and development centre, Halmstad, Sweden.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet, Rydberglaboratoriet för tillämpad naturvetenskap (RLAS). Spenshult research and development centre, Halmstad, Sweden | Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden.
    Aili, Katarina
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Hälsa och idrott. Spenshult research and development centre, Halmstad, Sweden.
    Bremander, Ann
    Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden | Spenshult research and development centre, Halmstad, Sweden | University of Southern Denmark, Department of Regional Health Research, Odense, Denmark.
    Bergman, Stefan
    Spenshult research and development centre, Halmstad, Sweden | Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden | The Sahlgrenska Academy, University of Gothenburg, Primary Health Care Unit, Department of Public Health and Community Medicine, Institute of Medicine, Gothenburg, Sweden.
    Metabolic factors associated to clinical hand osteoarthritis in individuals with knee pain2020Ingår i: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 79, nr Suppl. 1, s. 1734-1734Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: There is some evidence supporting associations between metabolic factors, clinical hand osteoarthritis (OA) and radiographic knee OA. However, more studies are needed regarding early knee OA.

    Objectives: The aim was to study associations between metabolic factors and clinical hand OA at baseline in a cohort of individuals with knee pain, with and without radiographic knee OA.

    Methods: In an ongoing five-year longitudinal study of knee pain, hand OA was assessed by clinical examinations in 296 of the included individuals at baseline [1]. BMI, waist circumference (WC) and blood pressure was measured. Body composition was assessed with Inbody 770. Fasting plasma glucose, triglycerides, cholesterol, HDL-and LDL-cholesterol and HbA1c was analysed. Metabolic syndrome (MetS)was present if central obesity (WC ≥94 cm in men and ≥80cm in women) plus any two of the following factors: raised blood pressure (systolic blood pressure ≥ 130 or diastolic blood pressure ≥ 85 mm Hg or treatment of hypertension), raised triglycerides (≥ 1.7 mmol/L or specific treatment), reduced HDL-cholesterol (men < 1.03 mmol/L and women < 1.29 mmol/L or specific treatment), raised glucose (glucose ≥ 5.6 mmol/L, or type 2 diabetes). Hand strength and self-reported disability of the arm, shoulder and hand (quickDASH) was assessed.

    The individuals were divided according to having clinical hand OA or not, according to Altman [1]. The associations between background factors and clinical hand OA were calculated by crude logistic regression analyses, adjusting for age and sex.

    Results: Fifty-five percent of the individuals in the study was overweight or obese, 40% had MetS and 23% had radiographic knee OA. In total 34% of the individuals had clinical hand OA. The group with hand OA were older, had higher proportion of body fat, fasting plasma glucose, HbA1C, worse quickDASH score and lower hand strength, table 1. Clinical hand OA was significantly associated to higher age (OR 1.04, 95%CI 1.01-1.07), higher fasting plasma glucose (1.56, 1.05-2.30), worse quickDASH (1.04, 1.02-1.06) and lower hand strength (0.99, 0.99 -0.998), but not to proportion of body fat and HbA1c.

    Conclusion: In this cross-sectional study, the only metabolic factor associated with clinical hand OA was fasting plasma glucose. Contrary to other studies, there were no gender differences found. The association between development of clinical hand OA and metabolic factors in individuals with knee pain need to be further assessed in longitudinal studies.

  • 22.
    Andersson, Maria L.E.
    et al.
    Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden; Spenshult Research and Development Centre, Halmstad, Sweden.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. Spenshult Research and Development Centre, Halmstad, Sweden; Lund University, Lund, Sweden.
    Aili, Katarina
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Spenshult Research and Development Centre, Halmstad, Sweden.
    Bremander, Ann
    Spenshult Research and Development Centre, Halmstad, Sweden; Lund University, Lund, Sweden; University of Southern Denmark, Odense, Denmark.
    Kindberg, F.
    Spenshult Research and Development Centre, Halmstad, Sweden.
    Bergman, Stefan
    Spenshult Research and Development Centre, Halmstad, Sweden; Lund University, Lund, Sweden; The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Metabolic Factors Associated to Radiographic Knee Osteoarthritis in Individuals with Knee Pain2020Ingår i: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 79, nr Suppl. 1, s. 793-793Artikel i tidskrift (Refereegranskat)
  • 23.
    Andersson, Maria L.E.
    et al.
    Spenshult Research and Development Center, Halmstad, Sweden; Lund University, Lund, Sweden.
    Thoren, Emelie
    Spenshult Research and Development Center, Halmstad, Sweden.
    Sylwander, Charlotte
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Spenshult Research and Development Center, Halmstad, Sweden.
    Bergman, Stefan
    Spenshult Research and Development Center, Halmstad, Sweden; University of Gothenburg, The Sahlgrenska Academy, Gothenburg, Sweden.
    Associations Between Chronic Widespread Pain, Pressure Pain Thresholds and Leptin in Individuals with Knee Pain2022Konferensbidrag (Övrigt vetenskapligt)
  • 24.
    Andersson, Maria L.E.
    et al.
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. Spenshult Research and Development Centre, Halmstad, Sweden; Lund University, Lund, Sweden.
    Thorén, Emelie
    Spenshult Research and Development Centre, Halmstad, Sweden.
    Sylwander, Charlotte
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Spenshult Research and Development Centre, Halmstad, Sweden.
    Bergman, Stefan
    Spenshult Research and Development Centre, Halmstad, Sweden; University of Gothenburg, Gothenburg, Sweden.
    Associations between chronic widespread pain, pressure pain thresholds, leptin, and metabolic factors in individuals with knee pain2023Ingår i: BMC Musculoskeletal Disorders, E-ISSN 1471-2474, Vol. 24, nr 1, artikel-id 639Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: The aim was to study associations between chronic widespread pain, widespread pain sensitivity, leptin, and metabolic factors in individuals with knee pain. A secondary aim was to study these associations in a subgroup of individuals with normal BMI.

    METHOD: This cross-sectional study included 265 individuals. The participants were categorised into three different pain groups: Chronic widespread pain (CWP), chronic regional pain (ChRP), or no chronic pain (NCP). The pressure pain thresholds (PPTs) were assessed using computerised pressure algometry. Low PPTs were defined as having PPTs in the lowest third of all tender points. Leptin and metabolic factors such as BMI, visceral fat area (VFA), lipids, and glucose were also assessed.

    RESULT: Sixteen per cent reported CWP, 15% had low PPTs, and 4% fulfilled both criteria. Those who fulfilled the criteria for CWP were more often women, more obese, and had increased leptin levels. In logistic regression, adjusted for age and gender, leptin was associated with fulfilling criteria for CWP, OR 1.015 (95% CI 1.004-1.027, p = 0.008). In logistic regression, adjusted for age and gender, leptin was associated with low PPTs, OR 1.016 (95% CI 1.004-1.029, p = 0.012). Leptin was also associated with fulfilling both criteria, adjusted for age, sex, and visceral fat area (VFA), OR 1.030 (95% CI 1.001-1.060), p = 0.040.

    CONCLUSION: Leptin was associated with fulfilling the combined criteria for chronic widespread pain and low PPTs, even after adjusting for the visceral fat area (VFA). Longitudinal studies are needed to study the causal relationships between leptin and the development of widespread pain.

  • 25.
    Andersson, Maria L.E.
    et al.
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. Spenshult Research and Development Center, Halmstad, Sweden; Lund University, Lund, Sweden.
    Zimmerman, M.
    Helsingborg Hospital, Helsingborg, Sweden; Lund University, Lund, Sweden.
    Brogren, E.
    Lund University, Lund, Sweden; Skåne University Hospital, Lund, Sweden.
    Bergman, Stefan
    Spenshult Research and Development Center, Halmstad, Sweden; Lund University, Lund, Sweden; Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
    Strindberg, L.
    University of Gothenburg, Gothenburg, Sweden.
    Fryk, E.
    University of Gothenburg, Gothenburg, Sweden.
    Jansson, P. A.
    University of Gothenburg, Gothenburg, Sweden.
    Baseline levels of circulating galectin-1 associated with radiographic hand but not radiographic knee osteoarthritis at a two-year follow-up2024Ingår i: Osteoarthritis and Cartilage Open, E-ISSN 2665-9131, Vol. 6, nr 2, artikel-id 100455Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objective: We tested the potential of circulating galectin-1, interleukin (IL)-1 beta, IL-6, and tumour necrosis factor alpha (TNF alpha) levels at baseline in individuals with knee pain as biomarkers for development of radiographic knee and/or hand osteoarthritis (OA). Design: This study comprised 212 individuals with knee pain from the Halland osteoarthritis cohort (HALLOA). Clinical characteristics and serum/plasma levels of galectin-1, IL-1 beta, IL-6, and TNF alpha were measured at baseline, and knee and hand radiographs were obtained at a two-year follow-up. The predictive value of circulating inflammatory markers and clinical variables at baseline was assessed using multinominal logistic regression for those who developed radiographic OA in knees only (n ​= ​25), in hands only (n ​= ​40), and in both knees and hands (n ​= ​43); the group who did not develop OA (n ​= ​104) was used as reference. Correlations were assessed using Spearman's correlation coefficients. Results: As expected, age was identified as a risk factor for having radiographic knee and/or hand OA at the two-year follow-up. Baseline circulating galectin-1 levels did not associate with developing radiographic knee OA but associated with developing radiographic hand OA (odds ratio (OR) for a 20% increased risk: 1.14, 95% confidence interval (CI) 1.01–1.29) and both radiographic knee and hand OA (OR for a 20% increased risk: 1.18, 95% CI 1.05–1.30). However, baseline IL-1 beta, IL-6, and TNF alpha did not associate with developing radiographic knee and/or hand OA. Conclusion: Non-age adjusted circulating galectin-1 is superior to IL-6, IL-1 beta, and TNF alpha in predicting radiographic hand but not knee OA. © 2024 The Author(s)

  • 26.
    Andersson, S.
    et al.
    Länssjukhuset, Halmstad.
    Fridlund, Bengt
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    The aphasic person's views of the encounter with other people: a grounded theory analysis2002Ingår i: Journal of Psychiatric and Mental Health Nursing, ISSN 1351-0126, E-ISSN 1365-2850, Vol. 9, nr 3, s. 285-292Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Notes that being affected by aphasia influences the total life experience. The aim of this study was to generate a theoretical model, from a nursing perspective, of what 12 aphasic persons (aged 28-92 yrs old) experience in encounters with other people. Data were collected through interviews which adopted a biophysical, socio-cultural and psychological approach and then analyzed using grounded theory method. Two main categories emerged, namely: interaction and support. Encountered experiences led to (1) a feeling of having ability, (2) a feeling of being an outsider, and (3) a feeling of dejection or uncertainty. The feeling state was dependent on whether the interaction was obstructed or secure and on whether the support resulted in strengthened or impaired self-esteem. Therefore, nurses need to give support that enhances patients self-esteem and which results in them gaining a positive and realistic view of their aphasia, as well as involving those around them in this perspective. This then will give the possibility for the patient to turn the interaction process from an obstructed into a secure one.

  • 27.
    Andersson, Ulrika
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Helin, Ann-Sofi
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Ögonsjuksköterskors upplevelser av att använda sin specifika omvårdnadskunskap vid telefonrådgivning2013Självständigt arbete på avancerad nivå (magisterexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Telefonrådgivning är en vanlig vårdform. I en alltmer medicinskt och tekniskt utvecklad ögonsjukvård efterfrågas ögonsjuksköterskornas omvårdnadskompetens av både patienter, anhöriga och kollegor inom andra delar av sjukvården. Syftet med studien var att undersöka ögonsjuksköterskors upplevelser av att använda sin specifika omvårdnadskunskap vid telefonrådgivning inom ögonsjukvård. Studien genomfördes med en kvalitativ metod och data samlades in genom semistrukturerade intervjuer. Materialet analyserades med kvalitativ innehållsanalys. Resultatet visade att ögonsjuksköterskorna upplevde arbetet som utvecklande och utmanande. De såg sig själva som en lots i vården med en stor rådgivande funktion relaterat till sin specifika kunskap. De beskrev också en del svårigheter med att triagera via telefon. De önskade bättre bedömningsunderlag men var dock trygga med sina bedömningar och någon rädsla för anmälningar till tillsynsmyndighet framkom inte. De uttryckte även ett behov av utbildning inom samtalsmetodik. Ögonsköterskorna saknade tid för kollegiala reflektioner för att utveckla sin professionella hållning i arbetet med telefonrådgivningen

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  • 28.
    Andersson, Åsa
    et al.
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet. FoU Spenshult Spenshult Research and Development Centre, Spenshult Research and Development Centre, Halmstad, Sweden; Lund University, Dept. of Clinical Sciences, Section of Rheumatology, Lund, Sweden.
    Berthold, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Mogard, Elisabeth
    Lund University, Lund, Sweden.
    Torell, Anna
    Ängelholm Hospital, Ängelholm, Sweden.
    Olsson, M. Charlotte
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Serum Protein Response To A Single High-Intensity Interval Training Bout – Comparison Between Individuals With Spondyloarthritis And Healthy Controls2022Ingår i: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 81, nr Suppl 1, s. 780-781Artikel i tidskrift (Refereegranskat)
  • 29.
    Andersson, Åsa
    et al.
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Olsson, M. Charlotte
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Torell, Anna
    Ängelholm hospital, Ängelholm, Sweden.
    Mogard, Elisabeth
    Lund University, Skåne University Hospital, Lund, Sweden.
    Haglund, Emma
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    Effects on serum protein levels from one bout of high intensity interval training in individuals with axial spondyloarthritis and controlsManuskript (preprint) (Övrigt vetenskapligt)
    Abstract [en]

    Background: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease primarily affecting the axial skeleton causing pain, inflammation, and stiffness. Individuals with axSpA are at greater risk of developing cardiovascular disease, which can be counteracted by physical activity. High-intensity interval training (HIIT) has been shown to improve cardiovascular health, but the effect on disease activity and the level of inflammation in axSpA has been less studied. With the aim of investigating how levels of inflammatory cytokines, myokines, and protein markers for bone metabolism are acutely affected by one bout of HIIT, we studied serum from individuals with axSpA and healthy controls (HC).

    Methods: Ten participants with axSpA and 11 age- and sex-matched HC performed a single HIIT bout on a cycle ergometer: 4x4 minutes intervals with three minutes active rest in between. Blood samples were taken before and one hour after the HIIT bout. Serum proteins (IL-6, IL-17, IL-18, TNFa, CXCL-10, VEGF-A, BDNF, DKK-1, osteoprotegerin, osteocalcin, osteopontin, BMP-7, CRP) were analyzed with a Luminex system or ELISA. Descriptive data are presented as mean with standard deviation. A two-way ANOVA was used for comparisons.

    Results: A main effect from baseline to one hour post HIIT showed that both groups had a significant increase in serum levels (pg/ml) of IL-6: axSpA 2.2 (3.0) to 3.2 (1.8) and HC 0.4 (0.4) to 1.9 (2.0), p=0.03. VEGF-A (pg/ml) was significantly lower in the axSpA group: 159 (138) vs. HC 326 (184), p=0.03, but was not affected by the HIIT bout. BMP-7 (ng/ml) increased in both groups after the HIIT: axSpA 61.6 (13.1) to 75.2 (20.0) and HC 64.6 (20.8 to 75.0 (17.8), p<0.001. For the other proteins analyzed, there were no significant differences in serum concentrations between individuals with axSpA and HC, or within the two groups before and after one bout of HIIT.

    Conclusions: One acute bout of HIIT significantly increases the serum concentrations of IL-6 and BMP-7 after 1 hour in both individuals with axSpA and HC.

    © Research Square 2024

  • 30.
    Andreasson, Maria
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Ekstav Lilja, Lena
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Förebyggande av anestesirelaterad atelektasbildning.2011Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Atelektaser uppstår inom tio minuter hos 90 % av alla patienter som sövs och leder till försämrad syresättning men kan även leda till postoperativa lungkomplikationer. Syftet med studien var att beskriva hur anestesisjuksköterskan med olika ventilationsstrategier kan förebygga atelektasbildning under generell anestesi. Studien genomfördes som en litteraturstudie där 19 vetenskapliga artiklar granskades och analyserades. Resultatet visar att när 100 % syrgas ges under induktionen av anestesi ökar uppkomsten av atelektaser. Om positive end-expiratory pressure (PEEP) 6-10 cmH2O används tillsammans med 100 % syrgas motverkas detta. Det är mer oklart vilken effekt PEEP har efter induktionen av anestesi. PEEP bör kombineras med rekryteringsmanöver för att effektivt motverka atelektasbildning. Olika metoder för att genomföra rekryteringsmanöver finns beskrivna men gemensamt är att topptrycket ska nå upp till cirka 40 cmH2O. Efter induktionen kan anestesisjuksköterskan även förebygga uppkomst av atelektaser genom använda 40 % syrgas. I den kliniska verksamheten saknas ofta riktlinjer för vilken ventilationsstrategi som ska användas. För att kunna arbeta preventivt med att förebygga atelektasbildning måste anestesisjuksköterskan diskutera ventilationsstrategi med anestesiläkaren innan problem med syresättningen uppstår. För framtida forskning skulle det kunna vara av intresse att undersöka hur olika ventilationsinställningar påverkar patientens upplevelse under preoxygenering.

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  • 31.
    Antonacci, Grazia
    et al.
    National Institute of Health Research (NIHR), London, United Kingdom; Imperial College Business School, London, United Kingdom.
    Whitney, Julie
    King's College London, London, United Kingdom.
    Harris, Matthew
    Imperial College London, London, United Kingdom.
    Reed, Julie
    Högskolan i Halmstad, Akademin för hälsa och välfärd. Julie Reed Consultancy Ltd, London, United Kingdom.
    How do healthcare providers use national audit data for improvement?2023Ingår i: BMC Health Services Research, E-ISSN 1472-6963, Vol. 23, nr 1, artikel-id 393Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: Substantial resources are invested by Health Departments worldwide in introducing National Clinical Audits (NCAs). Yet, there is variable evidence on the NCAs’ effectiveness and little is known on factors underlying the successful use of NCAs to improve local practice. This study will focus on a single NCA (the National Audit of Inpatient Falls -NAIF 2017) to explore: (i) participants’ perspectives on the NCA reports, local feedback characteristics and actions undertaken following the feedback underpinning the effective use of the NCA feedback to improve local practice; (ii) reported changes in local practice following the NCA feedback in England and Wales. Methods: Front-line staff perspectives were gathered through interviews. An inductive qualitative approach was used. Eighteen participants were purposefully sampled from 7 of the 85 participating hospitals in England and Wales. Analysis was guided by constant comparative techniques. Results: Regarding the NAIF annual report, interviewees valued performance benchmarking with other hospitals, the use of visual representations and the inclusion of case studies and recommendations. Participants stated that feedback should target front-line healthcare professionals, be straightforward and focused, and be delivered through an encouraging and honest discussion. Interviewees highlighted the value of using other relevant data sources alongside NAIF feedback and the importance of continuous data monitoring. Participants reported that engagement of front-line staff in the NAIF and following improvement activities was critical. Leadership, ownership, management support and communication at different organisational levels were perceived as enablers, while staffing level and turnover, and poor quality improvement (QI) skills, were perceived as barriers to improvement. Reported changes in practice included increased awareness and attention to patient safety issues and greater involvement of patients and staff in falls prevention activities. Conclusions: There is scope to improve the use of NCAs by front-line staff. NCAs should not be seen as isolated interventions but should be fully embedded and integrated into the QI strategic and operational plans of NHS trusts. The use of NCAs could be optimised, but knowledge of them is poor and distributed unevenly across different disciplines. More research is needed to provide guidance on key elements to consider throughout the whole improvement process at different organisational levels. © 2023, The Author(s).

  • 32.
    Archer, Trevor
    et al.
    University of Gothenburg, Gothenburg, Sweden.
    Josefsson, Torbjörn
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Lindwall, Magnus
    University of Gothenburg, Gothenburg, Sweden.
    Effects of physical exercise on depressive symptoms and biomarkers in depression2014Ingår i: CNS & Neurological Disorders: Drug Targets, ISSN 1871-5273, E-ISSN 1996-3181, Vol. 13, nr 10, s. 1640-1653Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Regular physical exercise/activity has been shown repeatedly to promote positive benefits in cognitive, emotional and motor domains concomitant with reductions in distress and negative affect. It exerts a preventative role in anxiety and depressive states and facilitates psychological well-being in both adolescents and adults. Not least, several meta-analyses attest to improvements brought about by exercise. In the present treatise, the beneficial effects of exercise upon cognitive, executive function and working memory, emotional, self-esteem and depressed mood, motivational, anhedonia and psychomotor retardation, and somatic/physical, sleep disturbances and chronic aches and pains, categories of depression are discussed. Concurrently, the amelioration of several biomarkers associated with depressive states: hypothalamic-pituitary-adrenal (HPA) axis homeostasis, anti-neurodegenerative effects, monoamine metabolism regulation and neuroimmune functioning. The notion that physical exercise may function as "scaffolding" that buttresses available network circuits, anti-inflammatory defences and neuroreparative processes, e.g. brain-derived neurotrophic factor (BDNF), holds a certain appeal. © 2014 Bentham Science Publishers.

  • 33.
    Arnell, Erika
    et al.
    Högskolan i Halmstad, Akademin för hälsa och välfärd.
    Wahman, Linda
    Högskolan i Halmstad, Akademin för hälsa och välfärd.
    Specialistsjuksköterskors erfarenheter av omvårdnad vid suicidproblematik inom psykiatrisk hälso- och sjukvård2022Självständigt arbete på avancerad nivå (magisterexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Bakgrund: Specialistsjuksköterskor inom psykiatrisk hälso- och sjukvård möter dagligen patienter med suicidproblematik. Suicid ses som ett folkhälsoproblem och är ett komplext område att arbeta med. Syfte: var att beskriva specialistsjuksköterskors erfarenheter av omvårdnad vid suicidproblematik inom psykiatrisk hälso- och sjukvård. Metod: Kvalitativ design med induktiv ansats. Tolv semistrukturerade intervjuer analyserades enligt kvalitativ innehållsanalys. Resultat: I studien framkom tre kategorier “Behovet av kontinuerliga och enhetliga bedömningar för patientsäkerhet”, “Vikten av kollegial samverkan som grund för delaktighet” samt "Betydelsen av kompetens för att skapa trygghet”. I resultatet beskrevs specialistsjuksköterskans erfarenheter av att stundtals känna sig ensamma vid suicidriskbedömningar och därav betonades betydelsen av kollegialt samarbete. Specialistsjuksköterskornas erfarenheter var att kompetensen att möta patienter med suicidproblematik samt tiden att handleda kollegor var betydande för att omvårdnaden skulle vara trygg och säker. Specialistsjuksköterskor har en betydelsefull roll i mötet med patienter med suicidproblematik samt att förmedla kunskap till kollegor inom andra verksamheter. Konklusion: Tiden att finnas till för patienterna belystes som betydelsefull och vikten av utbildning och handledning beskrevs som betydande insatser i arbetet med patienter med suicidproblematik.

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  • 34.
    Arvidsson, Barbro
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Skärsäter, IngelaHögskolan Väst, Institutionen för omvårdnad, hälsa och kultur, Avd för sjuksköterskeutbildning.
    Psykiatrisk omvårdnad: att stödja hälsofrämjande processer2006Samlingsverk (redaktörskap) (Övrig (populärvetenskap, debatt, mm))
    Abstract [sv]

    oken, den första i sitt slag, har ett hälsofrämjande förhållningssätt både vad gäller att förhindra att psykisk ohälsa uppstår och att förhålla sig till personer som i någon mening drabbats av psykisk ohälsa. Syftet är att locka fram hälsofrämjande processer, att hitta hälsan i det sjuka. Författarna beskriver den vårdande insatsen, mötet och relationen mellan vårdare och patient/vårdtagare. Boken belyser också betydelsen av att övriga sociala relationer fungerar, såväl inom familjen som i övriga samhällslivet.

    (Beskrivning från förlaget)

  • 35.
    Arvidsson, Jenny
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Theodorsson, Linda
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS).
    Den fysiska aktivitetens betydelse för depression2011Självständigt arbete på grundnivå (högskoleexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Depression är en sjukdom där forskarna inte är överens om dess uppkomst. Forskning tyder på att depression år 2020 kommer att vara den näst vanligaste sjukdomen i världen. Fysisk aktivitet är viktigt för folkhälsan och påverkar individen såväl fysiskt som psykiskt. Syftet med denna litteraturstudie var att belysa sambandet mellan depression och fysisk aktivitet. Resultatet baseras på 14 artiklar som relaterar till syftet. Resultatet visade att de personer som är fysiskt aktiva har minskad risk att uppleva psykiska besvär som depression. Det finns även ett samband mellan hur mycket fysisk aktivitet som utförs och graden av depression. Sjuksköterskan har en viktig roll både vad det gäller förebyggande och lindrande av depression. Genom dialog med patienten kan fysisk aktivitet föreslås som ett komplement till den medicinska behandlingen. Det kan räcka med ett par promenader i veckan för att risken för uppkomst av depression samt depressionssymtomen hos dem som lider av depression skall minska. Om fler människor motionerar regelbundet skulle med största sannolikhet depressionsfrekvensen minska. Vidare forskning inom området samt implementering av den kunskap som finns bör göras. Det är viktigt att den positiva effekten av fysisk aktivitet vid depression når fram till alla professioner inom hälso- och sjukvården och att den implementeras i verksamheterna. Detta kan på sikt tillsammans med ytterligare forskning leda till att viss del av den medicinska behandlingen kan ersättas med fysisk aktivitet.

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  • 36.
    Arvidsson, Jessica
    et al.
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Wigforss-gruppen.
    Widén, Stephen
    Örebro University, Örebro, Sweden.
    Tideman, Magnus
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Wigforss-gruppen.
    New labour market - old gender roles: working life after school for young adults with intellectual disability in Sweden2014Ingår i: JARID: Journal of applied research in intellectual disabilities, ISSN 1360-2322, E-ISSN 1468-3148, Vol. 27, nr 4, s. 373-373Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Aim: Taking a gender perspective, this study explores and analyzes the labour market situation for 2745 gainfully employed men and women with an educational background in the Swedish upper secondary school for pupils with intellectual disability (ID).

    Method: This quantitative register study is based on the cross-classification of a newly created register and a two additional Swedish national registers. The analyses are based on logistic regression and chi-square tests.

    Results: Those who are employed after upper secondary school for pupils with ID are 70.8% men and 29.2% women. Both the road to work and the situation at work differs between men and women. Small private companies are the main employers in general, and for women the public sector is also a major employer. Men and women are mainly employed in traditionally “male” and “female” occupations. Also, salary levels and additional support from the welfare system differs between the sexes and within the different educational programs.

    Conclusion: Traditional gender roles of the labour market are clearly manifested among the people included in the study. Questions about the gender structure of the Swedish labour market and the impact of educational background on wage labour will be discussed.

  • 37.
    Arvidsson, Jessica
    et al.
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Wigforss-gruppen.
    Widén, Stephen
    Institution of Health and Medicine, Swedish Institute for Disability Research, Örebro University, Örebro, Sweden.
    Tideman, Magnus
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI), Wigforss-gruppen.
    Post-school options for young adults with intellectual disabilities in Sweden2015Ingår i: Research and Practice in Intellectual and Developmental Disabilities, ISSN 2329-7018, Vol. 2, nr 2, s. 180-193Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The aim of this article is to examine life after school for young adults with intellectual disabilities in Sweden. It identifies a snapshot of the post-school destination in 2011 of students of Swedish Upper Secondary Schools for Pupils with Intellectual Disability (Special Secondary Schools), who graduated between 2001 and 2011. This national registry study used personal identification numbers to link data for about 12,269 former students in the Halmstad University Register on Pupils with Intellectual Disability with data about labour market participation and service provision under the Swedish disability legislation (Swedish LSS Act, 1994). Results showed that the largest proportion (47%) of former students participated in disability day programs, known as “daily activities”; 22.4% were employed, most with some type of wage subsidy; and 6.6% participated in various types of further education programs. A sizeable group (24%) were described as being “elsewhere”, not engaged in employment, education, or disability day programs. The type of post-school occupation is associated with gender, the type of educational program undertaken at secondary school, and age. The authors found a high risk of young people with intellectual disabilities falling through safety-net welfare or post-school participation provisions. Even in a country such as Sweden, which has comprehensive post-school programs, almost a quarter of young adults with intellectual disabilities were socially excluded, without education, disability day programs, or employment. © 2015 Australasian Society for Intellectual Disability

  • 38.
    Arvidsson, Susann
    et al.
    FoU Centrum, Spenshult, Halmstad, Sverige & Hälsohögskolan, Jönköping, Sverige.
    Arvidsson, Barbro
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Fridlund, Bengt
    Hälsohögskolan, Jönköping, Sverige.
    Bergman, Stefan
    FoU Centrum, Spenshult, Halmstad, Sverige.
    Factors promoting health-related quality of life in patients with rheumatic diseases 12 months after rehabilitation2010Ingår i: Svenska Läkaresällskapets Riksstämma 2010: Program: Reumatologi, 2010, s. 3-3Konferensbidrag (Refereegranskat)
    Abstract [en]

    Rheumatic diseases have significant adverse impact on the individual from physical, mental and social aspects, resulting in a low estimation of health-related quality of life (HRQL). Patients with rheumatoid arthritis who receive a multi-disciplinary team-based care in a rheumatology clinic could get improved HRQL. Several factors can be supposed to promote health in patients with rheumatic diseases and in health-promoting work within the clinical practice it would be valuable to identify health factors that affect HRQL in a positive direction.

    This is a longitudinal cohort study in 185 patients with rheumatic diseases with test one week and 12 months after rehabilitation on a Swedish rheumatology clinic. HRQL was assessed by SF-36 together with suggested health factors (chronic musculoskeletal pain, sleep quality, food habits, exercise habits, leisure habits, sexual lust, sense of coherence (SOC), social support and socio-demographic variables). The association between SF-36 subscales and suggested health factors were estimated by OR and 95 % CI calculated by multivariable logistic regressions.

    Factors predicting better outcome in HRQL in one or several SF-36 subscales were being of younger ages or middle-ages, feeling painless, having good sleep structure, feeling rested after sleep, doing low effort of exercise more than twice a week, having strong SOC, having emotional support and practical assistance, having higher educational level, and having working capacity. The most important factors were having strong SOC, feeling rested after sleep, having working capacity, being of younger ages or middle-ages, and having no/small problem with sleep structure.

    The most important factors promoting HRQL in patients with rheumatic diseases 12 months after rehabilitation were having strong SOC, feeling rested after sleep, having working capacity, being of younger ages or middle-ages, and having no/small problem with sleep structure. These health factors are important to address in clinical work with rheumatic diseases to optimise treatment strategies.

  • 39.
    Arvidsson, Susann
    et al.
    Research and Development Centre, Spenshult hospital for rheumatic diseases, Oskarström, Sweden & School of Health Sciences and Social Work, Växjö University, Växjö, Sweden.
    Arvidsson, Barbro
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI). Gjøvik University College, Faculty of Nursing Science, Gjøvik, Norway.
    Fridlund, Bengt
    School of Health Sciences and Social Work, Växjö University, Växjö, Sweden.
    Bergman, Stefan
    Research and Development Centre, Spenshult hospital for rheumatic diseases, Oskarström, Sweden.
    Feeling rested predicts good health in subjects with and without chronic musculoskeletal pain2008Konferensbidrag (Refereegranskat)
  • 40.
    Arvidsson, Susann
    et al.
    FoU Centrum, Spenshult, Halmstad, Sverige & Hälsohögskolan, Jönköping, Sverige.
    Bergman, Stefan
    FoU Centrum, Spenshult, Halmstad, Sverige.
    Arvidsson, Barbro
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI). Gjøvik University College, Gjøvik, Norge.
    Fridlund, Bengt
    School of Health Sciences, Jönköping University, Jönköping, Sweden.
    Bengtsson-Tops, Anita
    School of Health Sciences & Social Work, Växjö University, Växjö, Sweden.
    Upplevelse av hälsobefrämjande egenvård vid reumatisk sjukdom2009Konferensbidrag (Refereegranskat)
    Abstract [en]

    Bakgrund

    Personer med reumatiska sjukdomar skattar sitt hälsostatus lågt. Hälsostatus och tron på den egna förmågan att kunna påverka hälsan påverkar i sin tur valet av egenvårdsbeteenden. Egenvårdsbeteenden är vanliga och kan förhindra försämrad hälsa och förlust av värdefull fysisk och psykisk aktivitet. Kunskaperna är små om hur personer med reumatiska sjukdomar upplever att utföra egenvård. Syftet är därmed att beskriva hur personer med reumatiska sjukdomar erfar att utföra egenvård för att nå hälsa.

    Metod

    Studien har en kvalitativ design med en fenomenlogisk ansats och en livsvärldsteoretisk grund. Data har samlats in genom ostrukturerade och öppna intervjuer med 12 personer med olika diagnostiserade reumatiska sjukdomar.

    Resultat

    Personer med reumatiska sjukdomar upplever att egenvård är ett sätt att leva och att det innebär att ständigt vara redo för att förstå och reagera på signaler från den levda kroppen. Egenvård upplevs som en inre dialog inom den levda kroppen, men också en yttre dialog med närmiljön. Egenvård beskrivs också som en maktkamp där personen strävar efter och tvingar sig att kämpa mot sjukdomen och dess konkreta konsekvenser. Egenvården kräver också att val görs. Avgörande för valet är att personen har tillit till sig själv och tror på sin egen förmåga att välja hälsobefrämjande egenvård. Personer med reumatiska sjukdomar prioriterar egenvård som upplevs som positiv och/eller ger en belöning till den levda kroppen.

    Sammanfattning

    Personer med reumatiska sjukdomar upplever egenvård som ett sätt att leva och det innebär att vara i beredskap för att förstå och reagera på signaler som den levda kroppen sänder ut. Egenvård kräver dialog, maktkamp och val. Denna kunskap bidrar till en mer fullständig förståelse av faktorer som från ett patientperspektiv är viktiga för hälsan vid kronisk reumatisk sjukdom.

  • 41.
    Arvidsson, Susann
    et al.
    FoU Centrum, Spenshult, Halmstad, Sverige & Hälsohögskolan, Jönköping, Sverige.
    Bergman, Stefan
    FoU Centrum, Spenshult, Halmstad, Sverige.
    Arvidsson, Barbro
    Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI). Gjøvik University College, Gjøvik, Norge.
    Fridlund, Bengt
    Hälsohögskolan, Jönköping, Sverige.
    Tingström, Pia
    Linköpings universitet, Linköping, Sverige.
    Psychometric Properties of the Swedish Rheumatic Disease Empowerment Scale, SWE-RES-232010Ingår i: Svenska Läkaresällskapets Riksstämma 2010: Program: Reumatologi, 2010, s. 3-3Konferensbidrag (Refereegranskat)
    Abstract [en]

    Empowerment is a central concept in a patient-focused rheumatology care. WHO describes empowerment as a process in which the person receives more control over decisions and actions that affect the own life and health. Today there is no Swedish empowerment instrument for rheumatic diseases created or transl[...]

    The already existing questionnaire, Swedish Diabetes Empowerment Scale (SWE-DES-23), was adapted for use in patients with rheumatic diseases by exchanging the word diabetes with rheumatic disease in all the questions. No items were added or removed. The adapted questionnaire was called SWE-RES-23. In 2009, 260 patients with rheumatic diseases from a rheumatology unit in the southwest of Sweden completed the questionnaire.

    In order to establish discriminant validity, a question about self-perceived health from SF-36 was used in addition to SWE-RES-23.

    Construct validity was tested by using exploratory factor analysis. In order to determine unidimensionality of the empowerment subscales, inter-item correlations were calculated. Internal consistency reliability was tested by the use of the Cronbach-α coefficient.

    The exploratory factor analysis resulted in five factors (empowerment subscales) with Eigenvalues >1 explaining 64.1% of the variance. The five empowerment subscales were: Goal achievement and overcoming barriers to goal achievement, Self-awareness, Managing stress, Assessing dissatisfaction and readiness to change, and Support for caring. The Cronbach-α values ranged from 0.59 to 0.91 and for the total score 0.92. All inter-item correlations were significant. Patients with very good and good self-reported health scored significantly higher on three empowerment subscales (Goal achievement, Self-awareness and Managing stress). The same patterns were seen in the other two empowerment subscales (Readiness to change and Support for change), but did not reach significance.

    The SWE-RES-23 was a first step in developing a questionnaire for assessment of empowerment of patients with rheumatic diseases. The questionnaire possesses acceptable validity and reliability. To fully validate the SWE-RES-23 further studies are needed, but the instrument is even now possible to use in empowerment education programmes for patients with rheumatic diseases.

  • 42.
    Asker-Arnason, Lena
    et al.
    Section of Logopedics, Phoniatrics and Audiology, Department of Clinical Sciences, Lund University.
    Wengelin, Åsa
    Centre for Languages and Literature, Department of Linguistics, Lund University.
    Sahlén, Birgitta
    Section of Logopedics, Phoniatrics and Audiology, Department of Clinical Sciences, Lund University.
    Process and product in writing: A methodological contribution to the assessment of written narratives in 8-12 year old Swedish children using ScriptLog2008Ingår i: Logopedics Phoniatrics Vocology, ISSN 1401-5439, Vol. 33, nr 3, s. 143-152Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Twenty-seven children, with typical language development (TLD), 8-10 years old and 10-12 years old, were assessed with keystroke-logging in order to investigate their narrative writing. Measures of the writing process and the written product were used. One purpose was to explore how children produce written narratives in on-line production, and to relate the writing process to the written product. The results showed that those children who produced the final text faster, also wrote stories that comprised of more words. In the group of older children, children with better narrative ability used less pause time than those with worse ability, and the girls were faster writers than the boys. We believe that keystroke-logging gives valuable information for the assessment of young children's writing and that it is a potentially valid assessment tool for children from about 10 years of age.

  • 43.
    Asker-Árnason, Lena
    et al.
    Lund University.
    Ibertsson, Tina
    Lund University.
    Wass, Malin
    Linköping University.
    Wengelin, Åsa
    Lund University.
    Sahlén, Birgitta
    Lund University.
    Picture-elicited written narratives, process and product, in 18 children with cochlear implants2010Ingår i: Communication Disorders Quarterly, ISSN 1525-7401, E-ISSN 1538-4837, Vol. 31, nr 4, s. 195-212Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The purpose of the study was to explore the narrative writing of 18 children, ages 11 to 19, with severe and profound hearing impairment who had cochlear implants (CI), compared with the performance of hearing children. Nine of the 18 children had prelingual deafness and 9 children had postlingual deafness. The hearing impairment was progressive in 11 children. The participants thus formed a heterogeneous group, which was split in two ways: according to age at testing and age at implantation. The narratives were collected by means of keystroke logging. The difference between the children with CI and the hearing children was most prominent for two measures: the percentage of pause time (in the group of children older than 13 years) and lexical density. Furthermore, the children implanted after 5 years of age performed more like the hearing children. This group consisted of children with postlingual deafness and also of children who were deafened progressively. Our interpretation is that these children benefited from the early linguistic input. Taking the whole group of participants into consideration, the results reflect linguistic and cognitive processing limitations in complex linguistic tasks like narration for the children with CI in comparison with their hearing peers.

  • 44.
    Assabie, Yaregal
    et al.
    Addis Ababa University, Department of Computer Science, Addis Ababa, Ethiopia .
    Bigun, Josef
    Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS), Intelligenta system (IS-lab).
    Ethiopic Character Recognition Using Direction Field Tensor2006Ingår i: The 18th International Conference on Pattern Recognition: proceedings : 20-24 August, 2006, Hong Kong, Los Alamitos, Calif.: IEEE Computer Society, 2006, s. 284-287Konferensbidrag (Refereegranskat)
    Abstract [en]

    Many languages in Ethiopia use a unique alphabet called Ethiopic for writing. However, there is no OCR system developed to date. In an effort to develop automatic recognition of Ethiopic script, a novel system is designed by applying structural and syntactic techniques. The recognition system is developed by extracting primitive structural features and their spatial relationships. A special tree structure is used to represent the spatial relationship of primitive structures. For each character, a unique string pattern is generated from the tree and recognition is achieved by matching the string against a stored knowledge base of the alphabet. To implement the recognition system, we use direction field tensor as a tool for character segmentation, and extraction of structural features and their spatial relationships. Experimental results are reported.

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  • 45.
    Assabie, Yaregal
    et al.
    Addis Ababa University, Department of Computer Science, Addis Ababa, Ethiopia .
    Bigun, Josef
    Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS), Intelligenta system (IS-lab).
    Multifont size-resilient recognition system for Ethiopic script2007Ingår i: International Journal on Document Analysis and Recognition, ISSN 1433-2833, E-ISSN 1433-2825, Vol. 10, nr 2, s. 85-100Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    This paper presents a novel framework for recognition of Ethiopic characters using structural and syntactic techniques. Graphically complex characters are represented by the spatial relationships of less complex primitives which form a unique set of patterns for each character. The spatial relationship is represented by a special tree structure which is also used to generate string patterns of primitives. Recognition is then achieved by matching the generated string pattern against each pattern in the alphabet knowledge-base built for this purpose. The recognition system tolerates variations on the parameters of characters like font type, size and style. Direction field tensor is used as a tool to extract structural features.

  • 46.
    Aswad, Sami
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet.
    The Role of Physical Activity in Irritable Bowel Syndrome A Systematic Review2023Självständigt arbete på avancerad nivå (magisterexamen), 20 poäng / 30 hpStudentuppsats (Examensarbete)
    Abstract [en]

    Irritable Bowel Syndrome (IBS) is a common condition in the family of functional gastrointestinal disorders where patients suffer from abdominal pain and irregular bowel habits. The relationship between physical activity and IBS has not been well explored particularly in the area of physical activity’s role in mitigating the risk and improving the symptoms.In this systematic review, a comprehensive search was done on PubMed and Science Direct in order to find articles that help understand the relationship between physical activity levels and IBS in two folds; first, if there is a correlation between low physical activity levels and IBS, and second, if IBS patients would attain benefits on their symptoms and quality of life by increasing their physical activity levels.15 articles were found matching the inclusion criteria and were reviewed whereby relevant data has been extracted and synthesized; and after being critically analyzed, it transpires that the evidence on low physical activity level as a risk factor in IBS is not conclusive and requires future studies that adopt standard and streamlined methodologies for diagnosing IBS and assessing physical activity levels. Prospective studies in particular are recommended for that purpose.On the other hand, for those who are already diagnosed with IBS, there is an important evidence that increasing physical activity levels leads to lighter symptoms and remarkable improvements in quality of life which proposes physical activity as a primary treatment option in IBS patients. Nevertheless, in order to reach a more comprehensive understanding and a greater level of certainty, future research is needed on the effects of resistance training as well as the responses of each IBS sub-type to increased physical activity.

  • 47.
    Atabaki-Pasdar, Naeimeh
    et al.
    Department of Clinical Sciences, Lund University, Malmö, Sweden.
    Ohlsson, Mattias
    Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS), CAISR Centrum för tillämpade intelligenta system (IS-lab). Department of Astronomy and Theoretical Physics, Lund University, Lund, Sweden.
    Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts2020Ingår i: PLoS Medicine, ISSN 1549-1277, E-ISSN 1549-1676, Vol. 17, nr 6, artikel-id e1003149Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D). Early diagnosis of NAFLD is important, as this can help prevent irreversible damage to the liver and, ultimately, hepatocellular carcinomas. We sought to expand etiological understanding and develop a diagnostic tool for NAFLD using machine learning. Methods and findings We utilized the baseline data from IMI DIRECT, a multicenter prospective cohort study of 3,029 European-ancestry adults recently diagnosed with T2D (n = 795) or at high risk of developing the disease (n = 2,234). Multi-omics (genetic, transcriptomic, proteomic, and metabolomic) and clinical (liver enzymes and other serological biomarkers, anthropometry, measures of beta-cell function, insulin sensitivity, and lifestyle) data comprised the key input variables. The models were trained on MRI-image-derived liver fat content (<5% or ≥5%) available for 1,514 participants. We applied LASSO (least absolute shrinkage and selection operator) to select features from the different layers of omics data and random forest analysis to develop the models. The prediction models included clinical and omics variables separately or in combination. A model including all omics and clinical variables yielded a cross-validated receiver operating characteristic area under the curve (ROCAUC) of 0.84 (95% CI 0.82, 0.86; p < 0.001), which compared with a ROCAUC of 0.82 (95% CI 0.81, 0.83; p < 0.001) for a model including 9 clinically accessible variables. The IMI DIRECT prediction models outperformed existing noninvasive NAFLD prediction tools. One limitation is that these analyses were performed in adults of European ancestry residing in northern Europe, and it is unknown how well these findings will translate to people of other ancestries and exposed to environmental risk factors that differ from those of the present cohort. Another key limitation of this study is that the prediction was done on a binary outcome of liver fat quantity (<5% or ≥5%) rather than a continuous one. Conclusions In this study, we developed several models with different combinations of clinical and omics data and identified biological features that appear to be associated with liver fat accumulation. In general, the clinical variables showed better prediction ability than the complex omics variables. However, the combination of omics and clinical variables yielded the highest accuracy. We have incorporated the developed clinical models into a web interface (see: https://www.predictliverfat.org/) and made it available to the community. © This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

  • 48.
    Atiq, Ferdows
    et al.
    Erasmus MC, Rotterdam, Netherlands.
    Van De Wouw, Jens
    Erasmus MC, Rotterdam, Netherlands.
    Sorop, Oana
    Erasmus MC, Rotterdam, Netherlands.
    Heinonen, Ilkka
    Högskolan i Halmstad, Akademin för företagande, innovation och hållbarhet, Rydberglaboratoriet för tillämpad naturvetenskap (RLAS).
    De Maat, Moniek P. M.
    Erasmus MC, Rotterdam, Netherlands.
    Merkus, Daphne
    Erasmus MC, Rotterdam, Netherlands; Klinikum der Universität München, Munich, Germany; Deutsches Zentrum für Herz-Kreislauf-Forschung e. V., Berlin, Germany.
    Duncker, Dirk J.
    Erasmus MC, Rotterdam, Netherlands.
    Leebeek, Frank W. G.
    Erasmus MC, Rotterdam, Netherlands.
    Endothelial Dysfunction, Atherosclerosis, and Increase of von Willebrand Factor and Factor VIII: A Randomized Controlled Trial in Swine2021Ingår i: Thrombosis and Haemostasis, ISSN 0340-6245, E-ISSN 2567-689X, Vol. 121, nr 5, s. 676-686Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    All rights reserved.It is well known that high von Willebrand factor (VWF) and factor VIII (FVIII) levels are associated with an increased risk of cardiovascular disease. It is still debated whether VWF and FVIII are biomarkers of endothelial dysfunction and atherosclerosis or whether they have a direct causative role. Therefore, we aimed to unravel the pathophysiological pathways of increased VWF and FVIII levels associated with cardiovascular risk factors. First, we performed a randomized controlled trial in 34 Göttingen miniswine. Diabetes mellitus (DM) was induced with streptozotocin and hypercholesterolemia (HC) via a high-fat diet in 18 swine (DM + HC), while 16 healthy swine served as controls. After 5 months of follow-up, FVIII activity (FVIII:C) was significantly higher in DM + HC swine (5.85 IU/mL [5.00-6.81]) compared with controls (4.57 [3.76-5.40], p = 0.010), whereas VWF antigen (VWF:Ag) was similar (respectively 0.34 IU/mL [0.28-0.39] vs. 0.34 [0.31-0.38], p = 0.644). DM + HC swine had no endothelial dysfunction or atherosclerosis during this short-term follow-up. Subsequently, we performed a long-term (15 months) longitudinal cohort study in 10 Landrace-Yorkshire swine, in five of which HC and in five combined DM + HC were induced. VWF:Ag was higher at 15 months compared with 9 months in HC (0.37 [0.32-0.42] vs. 0.27 [0.23-0.40], p = 0.042) and DM + HC (0.33 [0.32-0.37] vs. 0.25 [0.24-0.33], p = 0.042). Both long-term groups had endothelial dysfunction compared with controls and atherosclerosis after 15 months. In conclusion, short-term hyperglycemia and dyslipidemia increase FVIII, independent of VWF. Long-term DM and HC increase VWF via endothelial dysfunction and atherosclerosis. Therefore, VWF seems to be a biomarker for advanced cardiovascular disease. © 2021 Georg Thieme Verlag. 

  • 49.
    Attema, Joanne L.
    et al.
    Immunology Unit, Institution for Experimental Medical Research, Lund University, Lund, Sweden.
    Pronk, Cornelis J. H.
    Immunology Unit, Institution for Experimental Medical Research, Lund University, Lund, Sweden.
    Norddahl, Gudmundur L.
    Immunology Unit, Institution for Experimental Medical Research, Lund University, Lund, Sweden.
    Nygren, Jens Martin
    Immunology Unit, Institution for Experimental Medical Research, Lund University, Lund, Sweden.
    Bryder, David
    Immunology Unit, Institution for Experimental Medical Research, Lund University, Lund, Sweden.
    Hematopoietic stem cell ageing is uncoupled from p16 INK4A-mediated senescence2009Ingår i: Oncogene, ISSN 0950-9232, E-ISSN 1476-5594, Vol. 28, nr 22, s. 2238-2243Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Somatic stem cells are ultimately responsible for mediating appropriate organ homeostasis and have therefore been proposed to represent a cellular origin of the ageing process-a state often characterized by inappropriate homeostasis. Specifically, it has been suggested that ageing stem cells might succumb to replicative senescence by a mechanism involving the cyclin-dependent kinase inhibitor p16(INK4A). Here, we tested multiple functional and molecular parameters indicative of p16(INK4A) activity in primary aged murine hematopoietic stem cells (HSCs). We found no evidence that replicative senescence accompanies stem cell ageing in vivo, and in line with p16(INK4A) being a critical determinant of such processes, most aged HSCs (>99%) failed to express p16(INK4A) at the mRNA level. Moreover, whereas loss of epigenetically guided repression of the INK4A/ARF locus accompanied replicative senescent murine embryonic fibroblasts, such repression was maintained in aged stem cells. Taken together, these studies indicate that increased senescence as mediated by the p16(INK4A) tumor suppressor has only a minor function as an intrinsic regulator of steady-state HSC ageing in vivo.

  • 50.
    Axelsson, Åsa B.
    et al.
    Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), Centrum för forskning om välfärd, hälsa och idrott (CVHI).
    Zettergren, Margaretha
    Institute of Nursing, Faculty of Health Caring Sciences, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
    Axelsson, Christer
    Institute of Nursing, Faculty of Health Caring Sciences, Sahlgrenska Academy at Göteborg University, Göteborg, Sweden.
    Good and bad experiences of family presence during acute care and resuscitation. What makes the difference?2005Ingår i: European Journal of Cardiovascular Nursing, ISSN 1474-5151, E-ISSN 1873-1953, Vol. 4, nr 2, s. 161-169Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background:

    Family presence (FP) in the resuscitation room is still controversial, and its appropriateness for patient and family has been discussed. We examined both positive and negative experiences in order to establish the reasons for the difference.

    Aim:

    The aim of the present literature review was to describe patients', relatives' and staff's opinions and experiences of FP during invasive procedures and resuscitation.

    Method:

    12 original papers, published between January 1995 and February 2003, were reviewed. Most patients and relatives agreed that they had positive experiences of FP. They described how FP enhanced the feeling of support and connectedness within the family. Family members believed that FP helped them in their grieving process. Most staff members without FP experience felt that FP would increase the risk of psychological distress for the family. Those who had participated in an FP programme believed that FP was not only beneficial for the family but also for staff.

    Conclusion:

    Family presence during resuscitation and acute care has the potential to enhance the care of the patient and to benefit everyone involved. However, implementation of FP during resuscitation must take account of potential problems.

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