Research on firm’s that already from inception see the whole world as a market and/or the whole world as a source to access resources, so called born globals. Many of these firms, build their competitive advantage on high-tech knowledge. Universities have shown to be an important actor, to create technology knowledge, and numerous studies have shown how new firms are created around universities, so called University Spin-offs (USOs). Earlier research has shown that some USOs are successful with their international growth strategies. This study aims to explore why some USOs are successful in their international growth strategy and some are not. 10 USO around the newly established Halmstad University in Sweden is investigated. Both USOs founded be students and researchers are included in the sample. This study shows the positive influence of a university for firm creation and international growth. The regional competence base has increased by the establishment of a local university, primarily by strengthening the regional human capital, but lately also by an increased amount of university research. This study has showed student entrepreneurs more successful in growth and international development than researcher entrepreneurs, which imply that further development of support for student entrepreneurship is fruitful to create international growing firms.