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Effects of physical exercise on depressive symptoms and biomarkers in depression
University of Gothenburg, Gothenburg, Sweden.
Halmstad University, School of Health and Welfare, Centre of Research on Welfare, Health and Sport (CVHI).
University of Gothenburg, Gothenburg, Sweden.
2014 (English)In: CNS & Neurological Disorders: Drug Targets, ISSN 1871-5273, E-ISSN 1996-3181, Vol. 13, no 10, 1640-1653 p.Article in journal (Refereed) Published
Abstract [en]

Regular physical exercise/activity has been shown repeatedly to promote positive benefits in cognitive, emotional and motor domains concomitant with reductions in distress and negative affect. It exerts a preventative role in anxiety and depressive states and facilitates psychological well-being in both adolescents and adults. Not least, several meta-analyses attest to improvements brought about by exercise. In the present treatise, the beneficial effects of exercise upon cognitive, executive function and working memory, emotional, self-esteem and depressed mood, motivational, anhedonia and psychomotor retardation, and somatic/physical, sleep disturbances and chronic aches and pains, categories of depression are discussed. Concurrently, the amelioration of several biomarkers associated with depressive states: hypothalamic-pituitary-adrenal (HPA) axis homeostasis, anti-neurodegenerative effects, monoamine metabolism regulation and neuroimmune functioning. The notion that physical exercise may function as "scaffolding" that buttresses available network circuits, anti-inflammatory defences and neuroreparative processes, e.g. brain-derived neurotrophic factor (BDNF), holds a certain appeal. © 2014 Bentham Science Publishers.

Place, publisher, year, edition, pages
Bussum: Bentham Science Publishers , 2014. Vol. 13, no 10, 1640-1653 p.
Keyword [en]
biomarkers, cognition, depression, emotion, exercise, HPA-axis, monoamines, motivation, neurodegeneration, neuroimmune function, physical activity, somatic, symptoms
National Category
Geriatrics
Identifiers
URN: urn:nbn:se:hh:diva-28308DOI: 10.2174/1871527313666141130203245ISI: 000348594400004PubMedID: 25470398Scopus ID: 2-s2.0-84924124549OAI: oai:DiVA.org:hh-28308DiVA: diva2:813245
Note

Financial support: Bliwa Foundation

Available from: 2015-05-22 Created: 2015-05-22 Last updated: 2017-03-16Bibliographically approved

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CiteExportLink to record
Permanent link

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Citation style
  • apa
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Language
  • de-DE
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