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Symptoms and Signs in Interpreting Gamma-hydroxybutyrate (GHB) Intoxication – An Explorative Study
Gothenburg University, Sahlgrenska Academy, the Institute of Health and Care Sciences, Gothenburg, Sweden.
Department of Anaesthesia and Intensive Care, Sahlgrenska University Hospital, Gothenburg, Sweden.
Police Department in Örebro County, Örebro, Sweden.
Halmstad University, School of Health and Welfare, Centre of Research on Welfare, Health and Sport (CVHI), Health promotion and disease prevention.
2014 (English)In: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, ISSN 1757-7241, E-ISSN 1757-7241, Vol. 22, 27Article in journal (Refereed) Published
Abstract [en]

Background

Acute poisoning with gamma-hydroxybutyrate (GHB) has been a serious medical and social problem in different parts of the world including Sweden. GHB is a drug of abuse which acts primarily as central nervous system (CNS) depressants. GHB has serious toxicity, although many young users do not recognise GHB as a dangerous drug. The aim of this pilot study was to explore how symptoms with risk of failure in vital functions would be valued among professionals that encounter GHB intoxication in the emergency phase.

Methods

A web-based survey focusing on the assessment of vital clinical signs for possible GHB intoxication using a numeric scale was carried out during April and May 2011. The participants, n 105, are all professionals who encounter GHB intoxicated in the emergency phase, but have different levels of training in GHB intoxication, mainly Registered Nurses (RNs) in southwest Sweden, employed in pre-hospital or emergency departments at somatic and most psychiatric health care facilities, as well as police officers who in their work come into contact with drug users. Responses in the survey were scored according to risk of GHB intoxication with serious failure of vital functions. The score value was then referred to a so-called evidence based priority (EBP) scale and analysed using descriptive statistics and Fisher's exact test.

Results

Cardiac arrest, coma, hypoxia, general convulsions, slow respiratory and heart rate and pale skin are symptoms with the highest risk of serious failure in vital physical functions and were predominantly recognised as such.

Conclusion

Despite the professionals' different levels of training in GHB intoxication, all of them were relatively well aware of and in accordance regarding the most risky symptoms. The interpretation score for the less risky symptoms and signs of GHB intoxication varied depending on their degree of training. The results should be viewed cautiously, as the size of the professional groups and their general knowledge of critical symptoms of GHB poisoning varied. © 2014 Stomberg et al.; licensee BioMed Central Ltd.

Place, publisher, year, edition, pages
London: BioMed Central, 2014. Vol. 22, 27
Keyword [en]
Gamma-hydroxybutyrate, GHB, Intoxication, Symptom, Sign
National Category
Nursing
Identifiers
URN: urn:nbn:se:hh:diva-25156DOI: 10.1186/1757-7241-22-27ISI: 000335464700001PubMedID: 24758357Scopus ID: 2-s2.0-84899989501OAI: oai:DiVA.org:hh-25156DiVA: diva2:714190
Note

Thanks are due to the University of Gothenburg, Sahlgrenska Academy, Institute of Health and Caring Science for in part funding and supporting the project.

Available from: 2014-04-25 Created: 2014-04-25 Last updated: 2017-03-17Bibliographically approved

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CiteExportLink to record
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Citation style
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