The objective of the present study is to present and test a generic framework for the operationalisation and conceptualisation of the constructs of mutual- and interactive-vulnerability in supply-chain dyads. The study involves a survey of a vehicle manufacturer and its most important suppliers. The results are analysed for an understanding of mutual- and interactive-vulnerability in such supply-chain dyads. The study identifies the dimensions of mutual- and interactive-vulnerability in supply-chain dyads. These can be used in management practice to analyse, describe and position different views of vulnerability. In addition, the study also presents a conceptual framework that distinguishes between the constructs of mutual- and interactive-vulnerability in supply-chain dyads. This research has contributed methodologically to the empirical measurement and evaluation of mutual- and interactive-vulnerability in supply-chain dyads. These constructs have not been explored simultaneously in previous research of the vulnerability construct.