A digital transformation of Swedish healthcare is currently taking place, and artificial intelligence (AI) is meant to solve many of the healthcare sector's challenges. The objective of this paper is to describe and analyze how the boundaries around the physicians' work could change when AI is implemented in healthcare and what boundary work actors on different levels in a healthcare system conduct. We conducted 26 semi-structured interviews with healthcare leaders and 18 with healthcare managers and professionals. The result shows that the leaders, healthcare managers, and healthcare professionals describe different types of boundary work in regard to the implementation of AI. The implementation of AI in healthcare could change the boundaries around the healthcare professionals’ work and generate new kinds of boundary work that could affect the implementation. These findings can inform both practice and policy.