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Prior electrocardiograms not useful for machine learning predictions of major adverse cardiac events in emergency department chest pain patients
Lund University, Lund, Sweden.
Skåne University Hospital, Lund, Sweden; Lund University, Lund, Sweden.
Lund University, Lund, Sweden.
Lund University, Lund, Sweden; Helsingborg Hospital, Helsingborg, Sweden.
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2024 (English)In: Journal of Electrocardiology, ISSN 0022-0736, E-ISSN 1532-8430, Vol. 82, p. 42-51Article in journal (Refereed) Published
Abstract [en]

At the emergency department (ED), it is important to quickly and accurately determine which patients are likely to have a major adverse cardiac event (MACE). Machine learning (ML) models can be used to aid physicians in detecting MACE, and improving the performance of such models is an active area of research. In this study, we sought to determine if ML models can be improved by including a prior electrocardiogram (ECG) from each patient. To that end, we trained several models to predict MACE within 30 days, both with and without prior ECGs, using data collected from 19,499 consecutive patients with chest pain, from five EDs in southern Sweden, between the years 2017 and 2018. Our results indicate no improvement in AUC from prior ECGs. This was consistent across models, both with and without additional clinical input variables, for different patient subgroups, and for different subsets of the outcome. While contradicting current best practices for manual ECG analysis, the results are positive in the sense that ML models with fewer inputs are more easily and widely applicable in practice. © 2023 The Authors

Place, publisher, year, edition, pages
Philadelphia, PA: Elsevier, 2024. Vol. 82, p. 42-51
Keywords [en]
Chest pain, Electrocardiograms, Emergency department, Machine learning, Major adverse cardiac event, Neural networks
National Category
Cardiac and Cardiovascular Systems
Identifiers
URN: urn:nbn:se:hh:diva-52486DOI: 10.1016/j.jelectrocard.2023.11.002ISI: 001129044900001PubMedID: 38006763Scopus ID: 2-s2.0-85182224199OAI: oai:DiVA.org:hh-52486DiVA, id: diva2:1831808
Funder
Swedish Research Council, 2019-00198Swedish Heart Lung Foundation, 2018-0173Vinnova, 2018-0192Available from: 2024-01-26 Created: 2024-01-26 Last updated: 2024-01-26Bibliographically approved

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Ohlsson, Mattias

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