In urban settings, the prevalence of traffic lights often leads to fluctuations in traffic patterns and increased energy utilization among vehicles. Recognizing this challenge, this research addresses the adverse effects of traffic lights on the energy efficiency of electric vehicles (EVs) through the introduction of a Multi-Intersections-Based Eco-Approach and Departure strategy (M-EAD). This innovative strategy is designed to enhance various aspects of urban mobility, including vehicle energy efficiency, traffic flow optimization, and battery longevity, all while ensuring a satisfactory driving experience. The M-EAD strategy unfolds in two distinct stages: First, it optimizes eco-friendly green signal windows at traffic lights, with a primary focus on minimizing travel delays by solving the shortest path problem. Subsequently, it employs a receding horizon framework and leverages an iterative dynamic programming algorithm to refine speed trajectories. The overarching objective is to curtail energy consumption and reduce battery wear by identifying the optimal speed trajectory for EVs in urban environments. Furthermore, the research substantiates the real-world efficacy of this approach through on-road vehicle tests, attesting to its viability and practicality in actual road scenarios. In the proposed case, the simulation results showcase notable achievements, with energy consumption reduced by 0.92% and battery wear minimized to a mere 0.0017%. This research, driven by the pressing issue of urban traffic energy efficiency, not only presents a solution in the form of the M-EAD strategy but also contributes to the fields of sustainable urban mobility and EV performance optimization. By tackling the challenges posed by traffic lights, this work offers valuable insights and practical implications for improving the sustainability and efficiency of urban transportation systems. © 2023 by the authors.