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Sleep interventions for children with attention deficit hyperactivity disorder (ADHD): A systematic literature review
Halmstad University, School of Health and Welfare.ORCID iD: 0000-0002-4341-660X
Halmstad University, School of Health and Welfare.ORCID iD: 0000-0003-4260-7399
Halmstad University, School of Health and Welfare. Psychiatry Halland, Halmstad, Sweden.ORCID iD: 0000-0003-1259-3993
Halmstad University, School of Health and Welfare.ORCID iD: 0000-0003-4438-6673
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2023 (English)In: Sleep Medicine, ISSN 1389-9457, E-ISSN 1878-5506, Vol. 102, p. 64-75Article, review/survey (Refereed) Published
Abstract [en]

Objective/background: Healthy sleep is particularly important for children with attention deficit hyperactivity disorder (ADHD), as sleep disturbances might aggravate disease symptoms. This review aims to synthesize and report evidence on the effectiveness of sleep interventions in increasing sleep, quality of life (QoL), and ADHD symptoms among children with ADHD. Patients/methods: The systematic literature review follows the Cochrane Collaboration methodology recommendations for literature reviews. Four databases were used based on the population, intervention, control and outcome (PICO) framework. Controlled trials with minimum 20 children in each group, aged 6–18, and published from 2005 and onwards were included. Results from the studies were reported in forest plots and three of the seven review outcomes were synthesized in meta-analyses. Results: The search identified 7710 records; of which 4808 abstracts were screened. After fulltext-screening of 99 papers, eight papers from five studies were included. The studies included behavioral sleep interventions and pharmacological interventions using melatonin and eszopiclone. For six of the seven outcomes, the effect sizes were small to moderate and the certainty of the evidence was low. For one outcome, sleep disturbances, the effect size was a moderate −0.49 standardized mean differences (95% confidence interval −0.65;-0.33), with a moderate certainty of evidence for the behavioral interventions for children aged 5–13 years with ADHD. Conclusions: This review identified few and heterogeneous studies. A moderate certainty of evidence for a moderate effect size was only obtained for sleep disturbances from the behavioral interventions. A low certainty of the evidence for a moderate effect size was found for the total sleep time from the pharmacological intervention using melatonin and one behavioral intervention, which indicates that these sleep interventions impact sleep quantity and quality among children with ADHD. © 2022 The Authors

Place, publisher, year, edition, pages
Amsterdam: Elsevier, 2023. Vol. 102, p. 64-75
Keywords [en]
Attention deficit hyperactivity disorder (ADHD), Children, Effectiveness, Sleep, Sleep interventions, Systematic literature review
National Category
Pediatrics
Identifiers
URN: urn:nbn:se:hh:diva-49904DOI: 10.1016/j.sleep.2022.12.021ISI: 000918992300001PubMedID: 36603513Scopus ID: 2-s2.0-85145676504OAI: oai:DiVA.org:hh-49904DiVA, id: diva2:1733179
Funder
Knowledge Foundation, 20200012Knowledge Foundation, 2019/152Forte, Swedish Research Council for Health, Working Life and Welfare, 2021-00664Available from: 2023-02-01 Created: 2023-02-01 Last updated: 2024-07-11Bibliographically approved

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Larsson, IngridAili, KatarinaLönn, MariaSvedberg, PetraNygren, Jens M.Ivarsson, AndreasJohansson, Pia

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