This paper uses the pre-renaissance philosopher Nicolas Cusanus (1401-1464) and his concepts of ratio (calculating rationality) and intellectus (a relation to not-knowing) to assist in understanding the differences between human and artificial intelligence. The intention is to contribute to the ongoing discussions and debate pertaining to AI implementation and use, arguing that philosophy can be of ample use when it comes to understanding different types of intelligence in the digital world. The presented conceptual framework outlines the human and the artificial intelligence in terms of their characteristics in relation to Cusa’s ratio and intellectus. This helps to apprehend the different forms of intelligence and, more specifically, their strengths and how they operate.