This paper reports preliminary efforts to canvas occupational therapists' opinions on occupational science research priorities. Findings, while not generalizable, suggest that occupational therapists are seeking to better understand how to influence the health of children and those with chronic conditions, as well as to have knowledge that underpins their practice in the use of occupation. Occupational science can support occupational therapy practitioners to meet future changes in the scope of occupational therapy practice. The initiative reported here is a small beginning in ensuring that occupational science fulfils its promise to inform the occupational therapy profession.