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Effects of physical exercise on depressive symptoms and biomarkers in depression
University of Gothenburg, Gothenburg, Sweden.
Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI).
University of Gothenburg, Gothenburg, Sweden.ORCID-id: 0000-0002-2066-6235
2014 (engelsk)Inngår i: CNS & Neurological Disorders: Drug Targets, ISSN 1871-5273, E-ISSN 1996-3181, Vol. 13, nr 10, s. 1640-1653Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Regular physical exercise/activity has been shown repeatedly to promote positive benefits in cognitive, emotional and motor domains concomitant with reductions in distress and negative affect. It exerts a preventative role in anxiety and depressive states and facilitates psychological well-being in both adolescents and adults. Not least, several meta-analyses attest to improvements brought about by exercise. In the present treatise, the beneficial effects of exercise upon cognitive, executive function and working memory, emotional, self-esteem and depressed mood, motivational, anhedonia and psychomotor retardation, and somatic/physical, sleep disturbances and chronic aches and pains, categories of depression are discussed. Concurrently, the amelioration of several biomarkers associated with depressive states: hypothalamic-pituitary-adrenal (HPA) axis homeostasis, anti-neurodegenerative effects, monoamine metabolism regulation and neuroimmune functioning. The notion that physical exercise may function as "scaffolding" that buttresses available network circuits, anti-inflammatory defences and neuroreparative processes, e.g. brain-derived neurotrophic factor (BDNF), holds a certain appeal. © 2014 Bentham Science Publishers.

sted, utgiver, år, opplag, sider
Bussum: Bentham Science Publishers , 2014. Vol. 13, nr 10, s. 1640-1653
Emneord [en]
biomarkers, cognition, depression, emotion, exercise, HPA-axis, monoamines, motivation, neurodegeneration, neuroimmune function, physical activity, somatic, symptoms
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Identifikatorer
URN: urn:nbn:se:hh:diva-28308DOI: 10.2174/1871527313666141130203245ISI: 000348594400004PubMedID: 25470398Scopus ID: 2-s2.0-84924124549OAI: oai:DiVA.org:hh-28308DiVA, id: diva2:813245
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Financial support: Bliwa Foundation

Tilgjengelig fra: 2015-05-22 Laget: 2015-05-22 Sist oppdatert: 2024-01-23bibliografisk kontrollert

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