hh.sePublikasjoner
Endre søk
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Plasma phospholipid fatty acid content is related to disease activity in ankylosing spondylitis
Division of Rheumatology, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Högskolan i Halmstad, Akademin för hälsa och välfärd, Centrum för forskning om välfärd, hälsa och idrott (CVHI).ORCID-id: 0000-0002-9291-9342
Division of Clinical Nutrition and Metabolism, Department of Public Health and Caring Science, Uppsala University, Uppsala, Sweden.
Division of Clinical Nutrition and Metabolism, Department of Public Health and Caring Science, Uppsala University, Uppsala, Sweden.
Vise andre og tillknytning
2012 (engelsk)Inngår i: Journal of Rheumatology, ISSN 0315-162X, E-ISSN 1499-2752, Vol. 39, nr 2, s. 327-333Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

OBJECTIVE: To investigate fatty acid composition in the diet, plasma phospholipids, and adipose tissue in a cohort of patients with ankylosing spondylitis (AS), and to determine their correlations to disease activity and blood lipids in a cross-sectional study. METHODS: Diet was assessed using a food frequency questionnaire in 66 patients with AS. Polyunsaturated fatty acids in plasma phospholipids and gluteal adipose tissue were measured using gas chromatography. Disease status was quantified using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), erythrocyte sedimentation rate (ESR), high sensitivity C-reactive protein, and proinflammatory cytokines. RESULTS: Diet did not correlate with disease activity assessed by the BASDAI, but there were negative correlations between the dietary intake of long-chain omega-3 fatty acids and ESR (rs = -0.27, p < 0.05). The plasma phospholipid content of arachidonic acid correlated significantly with the BASDAI score (rs = 0.39, p < 0.01). There were correlations between the intake of long-chain omega-3 fatty acids and high-density lipoproteins and serum triglycerides (rs = 0.26 and rs = -0.25, respectively, p < 0.05). CONCLUSION: There was a positive correlation between levels of arachidonic acid in plasma phospholipids and disease activity assessed by BASDAI in patients with AS. A Western diet does not appear to influence this correlation, but seems to affect blood lipids involved in atherogenic processes.

sted, utgiver, år, opplag, sider
Toronto: Journal of Rheumatology , 2012. Vol. 39, nr 2, s. 327-333
Emneord [en]
rheumatoid arthritis
HSV kategori
Identifikatorer
URN: urn:nbn:se:hh:diva-16806DOI: 10.3899/jrheum.110575ISI: 000301008200020PubMedID: 22174215Scopus ID: 2-s2.0-84856540464OAI: oai:DiVA.org:hh-16806DiVA, id: diva2:467962
Tilgjengelig fra: 2011-12-20 Laget: 2011-12-20 Sist oppdatert: 2017-04-24bibliografisk kontrollert

Open Access i DiVA

Fulltekst mangler i DiVA

Andre lenker

Forlagets fulltekstPubMedScopus

Personposter BETA

Johansson, Gunnar

Søk i DiVA

Av forfatter/redaktør
Johansson, Gunnar
Av organisasjonen
I samme tidsskrift
Journal of Rheumatology

Søk utenfor DiVA

GoogleGoogle Scholar

doi
pubmed
urn-nbn

Altmetric

doi
pubmed
urn-nbn
Totalt: 141 treff
RefereraExporteraLink to record
Permanent link

Direct link
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annet format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annet språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf