Public universities in Ghana are increasingly being urged annually by the National Council for Tertiary Education – a regulatory agency in Ghana – to publish their research outputs for national development. This paper examines research outputs from four public universities in Ghana that offer business programmes –Business, Management, and Accounting. The study sought to find out the number of publications made by lecturers in four universities from 1961 to 2017 and the types of method mostly used by business lecturers to conduct research.  Scopus Electronic Database was used to extract business articles published in four universities from 1961 to 2017. A total of 7,195 publications from four selected universities (University of Ghana (UG), University of Cape Coast (UCC), University of Education, Winneba (UEW) and Kwame Nkrumah University of Science and Technology (KNUST)) were generated. Systematic literature review was used for the study.  Business education lecturers from of Cape Coast had the highest number of articles (100) in the Scopus database. Conversely, University of Education, Winneba had the lowest number of articles (16). It was realized that most business lecturers (71%) in the four universities preferred Quantitative research methodology. The paper urges policy makers in Ghanaian public universities to put equal premium on quantitative, qualitative and case study driven research, as a way of generating novelty in research findings.