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Segmentation of 2D electrophoresis gel images for protein expression analysis
Högskolan i Halmstad, Akademin för informationsteknologi, Halmstad Embedded and Intelligent Systems Research (EIS). Chalmers University of Technology, Gothenburg, Sweden.
2005 (Engelska)Licentiatavhandling, sammanläggning (Övrigt vetenskapligt)
Ort, förlag, år, upplaga, sidor
Göteborg: Chalmers University of Technology ; Halmstad : School of Information Science, Computer and Electrical Engineering , 2005. , s. 26
Serie
Technical report, ISSN 1403-266X ; R028/2005
Nyckelord [en]
Two-dimensional gel electrophoresis, Image analysis, Image segmentation, Proteomics, Structure tensors, Spot detection, Spot segmentation
Nationell ämneskategori
Teknik och teknologier
Identifikatorer
URN: urn:nbn:se:hh:diva-714Libris ID: 10185544Lokalt ID: 2082/1063OAI: oai:DiVA.org:hh-714DiVA, id: diva2:237932
Presentation
(Engelska)
Anmärkning

Contains 2 papers

Tillgänglig från: 2007-06-04 Skapad: 2007-06-04 Senast uppdaterad: 2018-03-23Bibliografiskt granskad
Delarbeten
1. Protein spot detection by symmetry derivatives of Gaussians
Öppna denna publikation i ny flik eller fönster >>Protein spot detection by symmetry derivatives of Gaussians
2003 (Engelska)Ingår i: Image analysis, 13th Scandinavian Conference, SCIA 2003, Halmstad, Sweden, June 29 - July 2, 2003, Proceedings / [ed] Josef Bigun, Tomas Gustavsson (Eds), Springer , 2003, Vol. LNCS-2749, s. 520-525Konferensbidrag, Publicerat paper (Refereegranskat)
Abstract [en]

Two-dimensional gel electrophoresis is the preferred method for simultaneously separating and visualising thousands of proteins. An important part of the computer aided analysis of the proteome is the ability to automatically detect, identify, and quantify the proteins by means of automatic Image processing. We present a fast and sensitive method for protein spot detection using the Circular Symmetry Tensor. It is based upon the work of Bigun on Symmetry derivatives of Gaussians.

Ort, förlag, år, upplaga, sidor
Springer, 2003
Serie
Lecture Notes in Computer Science ; 2749
Nationell ämneskategori
Naturvetenskap
Identifikatorer
urn:nbn:se:hh:diva-14919 (URN)10.1007/3-540-45103-X_69 (DOI)000185178400069 ()2-s2.0-35248883560 (Scopus ID)978-3-540-40601-3 (ISBN)
Konferens
13th Scandinavian Conference, SCIA 2003, Halmstad, Sweden, June 29 - July 2, 2003
Tillgänglig från: 2011-04-04 Skapad: 2011-04-04 Senast uppdaterad: 2018-03-23Bibliografiskt granskad
2. Detection of spots in 2-d electrophoresis gels by symmetry features
Öppna denna publikation i ny flik eller fönster >>Detection of spots in 2-d electrophoresis gels by symmetry features
2005 (Engelska)Ingår i: Pattern recognition and data mining: Third International Conference on Advances in Pattern Recognition, ICAPR 2005, Bath, UK, August 22-25, 2005 : proceedings. Part I / [ed] Sameer Singh, Maneesha Singh, Chid Apte and Petra Perner, Berlin: Springer Berlin/Heidelberg, 2005, s. 436-445Konferensbidrag, Publicerat paper (Refereegranskat)
Abstract [en]

We have implemented an algorithm for detection and segmentation of protein spots in 2-D gel electrophoresis images using symmetry derivative features computed using low level image processing operations. The implementation was compared with a previously published Watershed segmentation and a commercial software. Our algorithm was found to yield segmentation results that were either better than or comparable to the other solutions while having fewer free parameters and a low computational cost. © Springer-Verlag Berlin Heidelberg 2005.

Ort, förlag, år, upplaga, sidor
Berlin: Springer Berlin/Heidelberg, 2005
Serie
Lecture Notes in Computer Science, ISSN 0302-9743 ; 3686
Nyckelord
Algorithms, Computational methods, Computer software, Electrophoresis, Gels, Image segmentation, Proteins
Nationell ämneskategori
Teknik och teknologier
Identifikatorer
urn:nbn:se:hh:diva-14928 (URN)000232247900047 ()2-s2.0-27244458675 (Scopus ID)978-3-540-28757-5 (ISBN)
Konferens
Third International Conference on Advances in Patten Recognition, ICAPR 2005, Bath, 22 August 2005 through 25 August 2005
Tillgänglig från: 2011-04-04 Skapad: 2011-04-04 Senast uppdaterad: 2018-03-23Bibliografiskt granskad

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