This article presents results from a project involving local practitioners in the construction of scenarios for a regional energy and transport system. The purpose is to demonstrate how sustainability transitions research can interact with local practice by means of socio-technical scenarios. Combining quantitative data with qualitative storylines, the article presents four scenarios, which describe different ways of using biogas, biodiesel and electricity in four different applications: city buses, inter-city buses, heavy-duty trucks and industrial processes. The article compares the four scenarios in terms of realization possibilities, energy efficiency and greenhouse gas reduction. Focusing on near-term realization on a commercial basis, the research findings suggest that collaborative scenario construction can be a useful strategy to manage conflicting agendas and engage key stakeholders in dialogues on transition pathways. The article concludes by presenting policy lessons for practice-oriented transition management. The lessons point to the importance of flexibility in system delineations, the critical timing of near-term scenarios, and the use of scenarios to outline local practitioners’ agency. © 2020 The Authors