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Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome
Turku PET Centre, Turku, Finland; University of Turku, Turku, Finland; Åbo Akademi University, Turku, Finland; Turku University Hospital, Turku, Finland.ORCID-id: 0000-0003-2770-5417
Turku PET Centre, Turku, Finland; University of Turku, Turku, Finland; Åbo Akademi University, Turku, Finland; Turku University Hospital, Turku, Finland.
Turku PET Centre, Turku, Finland; University of Turku, Turku, Finland; Åbo Akademi University, Turku, Finland; Turku University Hospital, Turku, Finland.
Turku PET Centre, Turku, Finland; University of Turku, Turku, Finland; Åbo Akademi University, Turku, Finland; Turku University Hospital, Turku, Finland.
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2022 (engelsk)Inngår i: Scandinavian Journal of Medicine and Science in Sports, ISSN 0905-7188, E-ISSN 1600-0838, Vol. 33, nr 3, s. 353-358Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Objective: The objective of the study was to investigate the associations of sedentary time, physical activity, and cardiorespiratory fitness with skeletal muscle glucose uptake (GU). Methods: Sedentary time and physical activity were measured with accelerometers and VO2max with cycle ergometry in 44 sedentary adults with metabolic syndrome. Thigh muscle GU was determined with [18F]FDG-PET imaging. Results: Sedentary time (β = −0.374), standing (β = 0.376), steps (β = 0.351), and VO2max (β = 0.598) were associated with muscle GU when adjusted for sex, age, and accelerometer wear time. Adjustment for body fat-% turned all associations non-significant. Conclusion: Body composition is a more important determinant of muscle GU in this population than sedentary time, physical activity, or fitness. © 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.

sted, utgiver, år, opplag, sider
West Sussex: John Wiley & Sons, 2022. Vol. 33, nr 3, s. 353-358
Emneord [en]
insulin resistance, physical activity, positron emission tomography, sedentary behavior, skeletal muscle
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Identifikatorer
URN: urn:nbn:se:hh:diva-49137DOI: 10.1111/sms.14287ISI: 000902940300001PubMedID: 36517882Scopus ID: 2-s2.0-85145087706OAI: oai:DiVA.org:hh-49137DiVA, id: diva2:1724924
Merknad

Funding: The Academy of Finland, University of Turku, Åbo Akademi University and Turku University Hospital.

Tilgjengelig fra: 2023-01-09 Laget: 2023-01-09 Sist oppdatert: 2023-02-17bibliografisk kontrollert

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Garthwaite, TaruLaitinen, KirsiKalliokoski, KariKnuuti, JuhaniHeinonen, Ilkka
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