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Lindholm, A., Bergman, S., Almquist-Tangen, G., Alm, B., Dahlgren, J. & Roswall, J. (2016). BMI Growth Patterns over First Five Years Differs between Children Being Obese and Overweight at Five Years of Age Compared with Normal/under Weight Children. In: : . Paper presented at 3rd International Conference on Nutrition & Growth, Vienna, Austria, March, 17-19, 2016.
Open this publication in new window or tab >>BMI Growth Patterns over First Five Years Differs between Children Being Obese and Overweight at Five Years of Age Compared with Normal/under Weight Children
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2016 (English)Conference paper, Oral presentation with published abstract (Refereed)
National Category
Medical and Health Sciences Clinical Medicine
Identifiers
urn:nbn:se:hh:diva-30689 (URN)
Conference
3rd International Conference on Nutrition & Growth, Vienna, Austria, March, 17-19, 2016
Note

Presentation no. 27

Available from: 2016-04-05 Created: 2016-04-05 Last updated: 2016-04-12Bibliographically approved
Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., . . . Wang, J. (2015). Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life. Cell Host and Microbe, 17(5), 690-703
Open this publication in new window or tab >>Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life
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2015 (English)In: Cell Host and Microbe, ISSN 1931-3128, E-ISSN 1934-6069, Vol. 17, no 5, p. 690-703Article in journal (Refereed) Published
Abstract [en]

The gut microbiota is central to human health, but its establishment in early life has not been quantitatively and functionally examined. Applying metagenomic analysis on fecal samples from a large cohort of Swedish infants and their mothers, we characterized the gut microbiome during the first year of life and assessed the impact of mode of delivery and feeding on its establishment. In contrast to vaginally delivered infants, the gut microbiota of infants delivered by C-section showed significantly less resemblance to their mothers. Nutrition had a major impact on early microbiota composition and function, with cessation of breast-feeding, rather than introduction of solid food, being required for maturation into an adult-like microbiota. Microbiota composition and ecological network had distinctive features at each sampled stage, in accordance with functional maturation of the microbiome. Our findings establish a framework for understanding the interplay between the gut microbiome and the human body in early life. © 2015 Elsevier Inc.

Place, publisher, year, edition, pages
Cambridge: Cell Press, 2015
National Category
Pediatrics
Identifiers
urn:nbn:se:hh:diva-29962 (URN)10.1016/j.chom.2015.04.004 (DOI)000356101500020 ()25974306 (PubMedID)2-s2.0-84929297936 (Scopus ID)
Funder
Knut and Alice Wallenberg FoundationSwedish Research CouncilNovo Nordisk
Available from: 2015-12-07 Created: 2015-12-07 Last updated: 2017-12-01Bibliographically approved
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0001-7269-648X

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