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Turkiewicz, AleksandraORCID iD iconorcid.org/0000-0003-1460-2275
Publications (3 of 3) Show all publications
Meesters, J., Bremander, A., Bergman, S., Petersson, I. F., Turkiewicz, A. & Englund, M. (2014). The risk for depression in patients with ankylosing spondylitis: a population-based cohort study. Arthritis Research & Therapy, 16(5), Article ID 418.
Open this publication in new window or tab >>The risk for depression in patients with ankylosing spondylitis: a population-based cohort study
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2014 (English)In: Arthritis Research & Therapy, ISSN 1478-6354, E-ISSN 1478-6362, Vol. 16, no 5, article id 418Article in journal (Refereed) Published
Abstract [en]

Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care.

Methods: The Skåne Healthcare Register comprises healthcare data of each resident in Region Skåne, Sweden (population 1.2 million), including ICD-10 diagnoses. Using physician coded consultation data from years 1999 to 2011, we calculated depression consultation rates for all AS patients. We obtained standardized depression-rate ratios by dividing the observed depression rate in AS patients by the expected rate based on the corresponding age- and sex-specific rates of depression in the general population seeking care. A ratio >1 equals a higher rate of depression among AS patients.

Results: The AS cohort consisted of 1738 subjects (65% men) with a mean age of 54 years. The reference population consisted of 967,012 subjects. During the 13-year observation period 10% (n = 172) of the AS cohort had a doctor-diagnosed depression compared to 6% (n = 105) to be expected. The standardized estimate of depression-rate ratio was 1.81 (95% confidence interval 1.44 to 2.24) in women men and 1.49 (1.20 to 1.89) in men.

Conclusions: The rate of doctor-diagnosed depression is increased about 80% in female and 50% in male AS patients. Future challenges are to timely identify and treat the AS patients who suffer from depression. © 2014 Meesters et al.; licensee BioMed Central Ltd.

Place, publisher, year, edition, pages
London: BioMed Central, 2014
National Category
Health Sciences Clinical Medicine
Identifiers
urn:nbn:se:hh:diva-27285 (URN)10.1186/s13075-014-0418-z (DOI)000349885900003 ()25209603 (PubMedID)2-s2.0-84910037660 (Scopus ID)
Funder
Swedish Research Council
Note

The authors acknowledge funding support from Swedish Research Council, Medical Faculty Lund University, and Region Skåne.

Available from: 2014-12-15 Created: 2014-12-15 Last updated: 2022-09-13Bibliographically approved
Haglund, E., Bremander, A., Petersson, I. F., Strömbeck, B., Bergman, S., Jacobsson, L. T. H., . . . Englund, M. (2011). Prevalence of spondyloarthritis and its subtypes in southern Sweden. Annals of the Rheumatic Diseases, 70(6), 943-948
Open this publication in new window or tab >>Prevalence of spondyloarthritis and its subtypes in southern Sweden
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2011 (English)In: Annals of the Rheumatic Diseases, ISSN 0003-4967, E-ISSN 1468-2060, Vol. 70, no 6, p. 943-948Article in journal (Refereed) Published
Abstract [en]

OBJECTIVE: To estimate the prevalence of spondyloarthritis and its subtypes.

METHODS: The Swedish healthcare organisation comprises a system where all inpatient and outpatient care is registered by a personal identifier. For the calendar years 2003-7, all residents aged ≥ 15 years in the southernmost county of Sweden (1.2 million inhabitants) diagnosed by a physician with spondyloarthritis (ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory arthritis associated with inflammatory bowel disease (Aa-IBD) or undifferentiated spondylarthritis (USpA)) were identified. To obtain valid point estimates of prevalence by the end of 2007, identification numbers were cross-referenced with the population register to exclude patients who had died or relocated.

RESULTS: The authors estimated the prevalence of spondyloarthritis (not including chronic reactive arthritis) as 0.45% (95% CI 0.44% to 0.47%). The mean (SD) age of patients with prevalent spondyloarthritis by the end of 2007 was 53 (15) years. Among the component subtypes, PsA accounted for 54% of cases, AS 21.4%, USpA 17.8% and Aa-IBD 2.3% with a prevalence of 0.25%, 0.12%, 0.10% and 0.015%, respectively. The remaining 6.4% had some form of combination of spondyloarthritis diagnoses. The prevalence of spondyloarthritis at large was about the same in men and women. However, the subtype PsA was more prevalent in women and AS was more prevalent in men.

CONCLUSION: In Sweden the prevalence of spondyloarthritis leading to a doctor consultation is not much lower than rheumatoid arthritis. PsA was the most frequent subtype followed by AS and USpA, and the two most frequent subtypes PsA and AS also display some distinct sex patterns.

Place, publisher, year, edition, pages
London: BMJ Books, 2011
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:hh:diva-22243 (URN)10.1136/ard.2010.141598 (DOI)000290149900011 ()21288961 (PubMedID)2-s2.0-79955792593 (Scopus ID)
Available from: 2013-05-21 Created: 2013-05-21 Last updated: 2017-12-06Bibliographically approved
Strömbeck, B., Jacobsson, L. T. H., Bremander, A., Englund, M., Heide, A., Turkiewicz, A. & Petersson, I. F. (2009). Patients with ankylosing spondylitis have increased sick leave—a registry-based case-control study over 7 yrs. Rheumatology, 48(3), 289-292
Open this publication in new window or tab >>Patients with ankylosing spondylitis have increased sick leave—a registry-based case-control study over 7 yrs
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2009 (English)In: Rheumatology, ISSN 1462-0324, E-ISSN 1462-0332, Vol. 48, no 3, p. 289-292Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: Using prospectively collected registry data to investigate sick leave (sickness benefit and sickness compensation) over a 7-yr period in patients with AS in comparison with population-based controls matched for age, sex and residential area.

METHODS: We investigated 122 (21 women and 101 men) outpatients with AS in South Sweden, born 1942 or later, from rheumatology specialist care for their sick leave during a 7-yr period. Mean (S.D.) age was 43 (11) yrs and mean (S.D.) disease duration was 20 (11) yrs. Two controls per case, matched for age, sex and residential area were selected from the Swedish National Population Register. Data concerning sick leave for cases and controls, based on the subjects' unique 10-digit personal identification number, were retrieved from the national register of the Swedish Social Insurance Agency.

RESULTS: More AS patients than controls were registered for sickness benefit (52 vs 36%, P < 0.01) and sickness compensation (42 vs 11%, P < 0.001). Cases had an increased risk for sick leave compared with controls with a relative risk of 1.8; 95% CI 1.5, 2.1; and cases had more days with sick leave than controls (median number of more days per year 30; 95% CI 2, 72).

CONCLUSIONS: Using the Swedish Social Insurance Agency's registers for sick leave, we found that patients with AS in rheumatology specialist care in South Sweden have an increased level of sick leave compared with controls. These population-based registers have a great potential for studies of the effects of different interventions on sick leave. © 2009 The Author(s).

Place, publisher, year, edition, pages
Oxford: Oxford University Press, 2009
Keywords
Ankylosing spondylitis, Sick leave, Work disability, Controlled study, Register
National Category
Medical and Health Sciences
Identifiers
urn:nbn:se:hh:diva-22238 (URN)10.1093/rheumatology/ken497 (DOI)000263603500018 ()19164425 (PubMedID)2-s2.0-61349202314 (Scopus ID)
Note

The project was funded by a grant from the Regional Health Service Authorities in Skåne (Region Skåne) and the Swedish Social Insurance Agency (Försäkringskassan). Funding to pay the Open Access publication charges for this article was provided by the Musculoskeletal Research Center, University Hospital, Lund, Sweden.

Available from: 2013-05-21 Created: 2013-05-21 Last updated: 2017-12-06Bibliographically approved
Identifiers
ORCID iD: ORCID iD iconorcid.org/0000-0003-1460-2275

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